TABLE 3.

Propensity Score Matched Study Cohorts: HCRU and Associated Costs per Patient per Year During the Follow-up Period

	Apixaban n = 7,107 Mean (SD) Median	Warfarin n = 7,107 Mean (SD) Median	P Valuea
All causes
Inpatient
Number of hospitalizations	0.7 (2.1) 0	1.1 (2.9) 0	< 0.001
Hospital length of stay (days)	4.0 (19.8) 0	7.1 (25.6) 0	< 0.001
Total inpatient cost ($)	8,327 (34,325) 0	14,296 (49,994) 0	< 0.001
Outpatient
Number of outpatient claims	32.7 (31.0) 24	51.0 (37.7) 42	< 0.001
Total outpatient cost ($)	9,655 (16,922) 4,158	11,469 (19,582) 5,295	< 0.001
Number of office visit claims	16.9 (14.4) 14	24.9 (20.4) 21	< 0.001
Office visit cost ($)	2,150 (4,583) 1,333	2,358 (5,168) 1,433	0.01
Number of emergency room claims	1.8 (4.3) 0	2.4 (5.3) 0	< 0.001
Emergency room cost ($)	864 (2,715) 0	1,155 (3,817) 0	< 0.001
Outpatient hospital claims	6.8 (14.0) 3	11.4 (19.3) 4	< 0.001
Outpatient hospital cost ($)	3,782 (11,751) 354	3,515 (11,264) 384	0.17
Other outpatient claims	11.7 (22.8) 4	20.4 (30.8) 9	< 0.001
Other outpatient cost ($)	2,858 (9,159) 204	4,441 (12,723) 458	< 0.001
Prescription
Number of outpatient prescription claims	53.0 (36.4) 46	54.7 (39.2) 48	0.006
Total outpatient prescription cost ($)	5,159 (5,909) 4,296	2,867 (4,857) 1,545	< 0.001
Total medical cost ($; inpatient + outpatient)	17,981 (43,039) 4,878	25,766 (59,220) 6,793	< 0.001
Total medical and prescription cost	23,141 (43,595) 10,452	28,633 (59,650) 9,967	< 0.001
Bleeding-related
Total medical cost ($; inpatient + outpatient)	2,101 (17,867) 0	3,963 (27,424) 0	< 0.001
Stroke-related
Total medical cost ($; inpatient + outpatient)	652 (7,192) 0	1,178 (11,695) 0	0.001

^aP values were calculated for the differences in mean values.

HCRU = health care resource utilization; SD = standard deviation.