TABLE 2.
Pre-index Period | Post-index Period | |||||
Non-Treatment-Regimen Failures n = 1,255 | Treatment-Regimen Failures n = 891 | Difference P Valuea | Non-Treatment-Regimen Failures n = 1,255 | Treatment-Regimen Failures n = 891 | Difference P Valueb | |
---|---|---|---|---|---|---|
Outpatient | ||||||
Patients with outpatient physician visit, n (%) | 1,254 (99.9) | 891 (100.0) | 0.399 | 1,250 (99.6) | 879 (98.7) | 0.015 |
Outpatient visits (all), mean (SD) | 16.2 (16.1) | 17.9 (16.2) | 0.013 | 13.4 (12.3) | 17.2 (15.0) | < 0.001 |
Outpatient costs, US $ | - | - | 0.002 | - | - | < 0.001 |
Mean (SD) | 3,549 (6,298) | 4,470 (7,387) | - | 4,026 (8,126) | 6,926 (14,535) | - |
Median | 1,682 | 2,121 | - | 1,473 | 2,435 | - |
Inpatient | ||||||
Patients with inpatient admission, n (%) | 44 (3.5) | 46 (5.2) | 0.059 | 62 (4.9) | 66 (7.4) | 0.017 |
Inpatient admissions, mean (SD) | 0.2 (1.1) | 0.3 (1.5) | 0.050 | 0.3 (2.1) | 0.6 (2.7) | 0.012 |
Inpatient costs, US $ | - | - | 0.024 | - | - | 0.301 |
Mean (SD) | 507 (3,694) | 1,046 (7,198) | - | 1,092 (13,856) | 1,688 (8,588) | - |
Median | 0 | 0 | - | 0 | 0 | - |
Pharmacy, U.S. $ | ||||||
Pharmacy costs | - | - | 0.651 | - | - | < 0.001 |
Mean (SD) | 2,580 (3,757) | 2,508 (3,550) | - | 25,641 (11,712) | 19,398 (13,291) | - |
Median | 1,389 | 1,388 | - | 25,070 | 17,405 | - |
Total health care costs, U.S. $ | - | - | 0.002 | - | - | 0.002 |
Mean (SD) | 6,637 (8,908) | 8,024 (11,576) | - | 30,759 (19,866) | 28,012 (21,583) | - |
Median | 3,938 | 4,583 | - | 27,943 | 24,494 | - |
aCosts during pre-index period were compared using analysis of variance.
bCosts during post-index period were analyzed using propensity score bin bootstrapping adjusted for age, gender, insurance type, Charlson Comorbidity Index, total net cost in prior period, comorbidities, medications, and provider types.
SD = standard deviation; U.S. = United States.