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. 2016 Aug;22(8):10.18553/jmcp.2016.22.8.901. doi: 10.18553/jmcp.2016.22.8.901

TABLE 4.

Statin Dose Intensity Before and After 2013 Cholesterol Guidelinea

Preguideline Postguideline Change Std. Diff. (%)b
ASCVD, ≥75 years (n = 87,519)
    None 11,010 (12.6) N/A N/A N/A
    Low 13,932 (15.9) 15,090 (17.2) 1,158 (1.3) 3.5
    Moderate 48,943 (55.9) 54,578 (62.4) 5,635 (6.4) 13.3
    High 13,634 (15.6) 17,851 (20.4) 4,217 (4.8) 12.5
ASCVD, > 75 years (n = 54,998)
    None 5,501 (10.0) N/A N/A N/A
    Low 11,248 (20.5) 12,302 (22.4) 1,054 (1.9) 4.6
    Moderate 32,210 (58.6) 35,230 (64.1) 3,020 (5.5) 11.3
    High 6,039 (11.0) 7,466 (13.6) 1,427 (2.6) 7.9
    Moderate or high 38,249 (69.5) 42,696 (77.6) 4,447 (8.1) 18.4
DM (n = 159,195)
    None 22,876 (14.4) N/A N/A N/A
    Low 29,451 (18.5) 32,687 (20.5) 3,236 (2.0) 5.0
    Moderate 89,877 (56.5) 102,576 (64.4) 12,699 (8.0) 16.2
    High 16,991 (10.7) 23,932 (15.0) 6,941 (4.4) 12.9
    Moderate or high 106,868 (67.1) 126,508 (79.5) 19,640 (12.3) 28.3

Note: Values are represented as number (%) unless noted otherwise.

a Rates are aggregate rates and are restricted to only those patients who were on statin therapy 1 year after the 2013 cholesterol guideline.

b A standardized difference of >10% was considered a significant imbalance between proportions.

ASCVD = atherosclerotic cardiovascular disease; DM = diabetes mellitus; N/A = not applicable; Std. Diff. = standardized difference.