TABLE 5.
Patient-Level Intensification of Statin Therapy Before and After Cholesterol Guidelinea
| Statin Intensity Preguideline | Statin Intensity Postguideline | Change to Guideline Dose | Change to Nonguideline Dose | |||
| Low | Moderate | High | ||||
| ASCVD, ≤ 75 years | No statin | 2,470 (22.4) | 6,715 (61.0) | 1,825 (16.6) | 1,825 (16.6) | 2,990 |
| Low | 8,519 (61.2) | 5,011 (36.0) | 402 (2.9) | 402 (2.9) | ||
| Moderate | 3,982 (8.1) | 39,981 (81.7) | 4,980 (10.2) | 4,980 (10.2) | ||
| High | 119 (0.9) | 2,871 (21.1) | 10,644 (78.1) | 7,207 | ||
| ASCVD, > 75 years | No statin | 1,371 (24.9) | 3,409 (62.0) | 721 (13.1) | 4,130 (75.1) | 3,045 |
| Low | 7,886 (70.1) | 3,196 (28.4) | 166 (1.5) | 3,362 (29.9) | ||
| Moderate | 2,979 (9.3) | 27,243 (84.6) | 1,988 (6.2) | 7,492 | ||
| High | 66 (1.1) | 1,382 (22.9) | 4,591 (76.0) | |||
| Diabetes mellitus | No statin | 5,651 (24.7) | 14,289 (62.5) | 2,936 (12.8) | 17,225 (75.3) | 8,346 |
| Low | 18,690 (63.5) | 10,063 (34.2) | 698 (2.4) | 10,761 (36.5) | ||
| Moderate | 8,159 (9.1) | 74,398 (82.8) | 7,320 (8.1) | 27,986 | ||
| High | 187 (1.1) | 3,826 (22.5) | 12,978 (76.4) | |||
Note: Values are represented as number (%) unless noted otherwise.
a Rates are for only those patients who were on statin therapy 1 year after the 2013 cholesterol guideline.
ASCVD = atherosclerotic cardiovascular disease.