TABLE 3.

Adjusted Adherence Outcomes for Oral DMT Cohorts^a

Parameter	OR (95% CI)	P Value
MPR ≥ 80%
Fingolimod	Reference
Dimethyl fumarate	0.18 (0.09-0.36)	< 0.001
Teriflunomide	0.19 (0.08-0.42)	< 0.001
PDC ≥80%
Fingolimod	Reference
Dimethyl fumarate	0.47 (0.33-0.67)	< 0.001
Teriflunomide	0.37 (0.23-0.59)	<0.001

^aAdherence outcomes were adjusted for region, gender, age, previous injectable/infused DMT use (yes/no), previous oral DMT use (yes/no), previous MS relapse (yes/no), and CCI score.

CCI = Charlson Comorbidity Index; CI = confidence interval; DMT = diseasemodifying therapy; MPR = medication possession ratio; MS = multiple sclerosis; OR = odds ratio; PDC = proportion of days covered.