Figure 1.

Chromatin mesoscale model. 50-nucleosome chromatin fiber with the enlarged basic unit (chromatosome) showing each element and the enlarged tri-nucleosome showing the connection between nucleosomes by linker DNA. Linker DNA is shown as red beads; histone tails as green (H3), yellow (H2A), red (H2B), and blue (H4) beads; LHs are shown as orange (globular head) and cyan (C-terminal domain) beads; and nucleosome cores are shown with their distributed charge beads. To see this figure in color, go online.