TABLE 3.
Odds Ratios and 95% CIs from Model 10, Separately Within Each Stratum of Days Supply
| Characteristic | ≤ 30 Days Supply | > 30 Days Supply |
|---|---|---|
| Adherent month 1 | 2.43 (1.41-4.19) | a |
| Adherent month 2 | 3.22 (3.10-3.35) | 3.23 (1.28-8.16) |
| Adherent month 3 | 4.65 (4.47-4.84) | 2.65 (1.98-3.56) |
| Adherence to chronic disease medications (reference = few) | ||
| Adherent to most | 1.37 (1.31-1.43) | 1.23 (1.10-1.37) |
| Not taking any chronic disease medications | 1.22 (1.15-1.30) | 1.02 (0.89-1.19) |
| Full statin adherence in baseline period | 2.69 (2.59-2.80) | 2.24 (2.04-2.45) |
| Declining statin adherence in baseline period | 1.17 (1.13-1.22) | 1.00 (0.90-1.11) |
| Female gender | 0.92 (0.89-0.97) | 0.91 (0.84-0.99) |
| Age | 1.01 (1.01-1.01) | 1.00 (1.00-1.01) |
| Percentage of blacks in ZIP code | 1.00 (1.00-1.00) | 1.00 (1.00-1.00) |
| Percentage with high school education or greater in ZIP code | 1.01 (1.00-1.01) | 1.00 (1.00-1.01) |
| Median household income in ZIP code (reference ≤ $50,000) | ||
| $50,000-$99,999 | 1.14 (1.08-1.20) | 1.16 (1.02-1.31) |
| $100,000+ | 1.37 (1.27-1.48) | 1.487 (1.26-1.76) |
| Number of chronic conditions | 1.03 (1.01-1.06) | 0.96 (0.91-1.02) |
| Index statin | ||
| Index statin generic (reference = atorvastatin) | ||
| Fluvastatin | 1.13 (0.86-1.51) | 1.44 (0.87-2.36) |
| Lovastatin | 0.82 (0.74-0.90) | 0.90 (0.72-1.12) |
| Pravastatin | 0.67 (0.62-0.73) | 0.76 (0.64-0.90) |
| Rosuvastatin | 0.80 (0.76-0.86) | 0.84 (0.74-0.96) |
| Simvastatin | 0.80 (0.76-0.86) | 0.84 (0.74-0.95) |
| Pitavastatin | 0.53 (0.40-0.69) | 0.67 (0.33-1.37) |
| High-intensity dose | 1.00 (0.94-1.05) | 1.02 (0.91-1.15) |
| Copayment (reference ≤ $6.40) | ||
| $6.40-$14.99 | 0.95 (0.91-1.00) | 1.10 (0.93-1.29) |
| $15.00-$34.99 | 0.99 (0.94-1.05) | 1.04 (0.90-1.21) |
| $35.00+ | 0.85 (0.80-0.91) | 0.97 (0.83-1.12) |
| Number of cardiovascular diagnoses | 0.99 (0.97-1.01) | 1.01 (0.97-1.05) |
| Charlson comorbidity score | 1.01 (0.99-1.04) | 1.01 (0.96-1.05) |
| Number of hospitalizations | 1.01 (0.98-1.04) | 0.88 (0.77-0.99) |
| Total hospitalization length of stay | 1.00 (1.00-1.00) | 1.00 (0.99-1.01) |
| Number of outpatient visits | 1.01 (1.01-1.02) | 1.00 (0.99-1.01) |
| Number of unique hospitalizations | 0.99 (0.98-1.00) | 1.01 (0.99-1.02) |
| Postsurgical aortocoronary bypass | 0.94 (0.76-1.16) | 1.37 (0.88-2.14) |
| Recent CABG | 1.28 (0.73-2.25) | 0.34 (0.09-1.28) |
| Previous CABG | 0.90 (0.47-1.74) | 1.54 (0.31-7.64) |
| Recent percutaneous coronary intervention | 0.87 (0.64-1.18) | 1.09 (0.42-2.82) |
| Previous percutaneous coronary intervention | 0.81 (0.59-1.12) | 1.23 (0.48-3.12) |
| Angina | 0.77 (0.22-2.74) | - |
| Atrial fibrillation | 0.96 (0.70-1.31) | 1.43 (0.73-2.79) |
| Chest pain | 0.88 (0.81-0.95) | 1.06 (0.89-1.26) |
| Congestive heart failure | 0.68 (0.39-1.18) | 2.09 (0.25-17.67) |
| Hypertension | 1.16 (1.11-1.22) | 1.30 (1.17-1.44) |
| Ischemic heart disease | 1.14 (1.06-1.23) | 1.14 (0.97-1.33) |
| Myocardial infarction | 0.81 (0.56-1.18) | 4.14 (0.51-33.45) |
| Peripheral vascular disease | 1.22 (0.87-1.70) | 0.76 (0.41-1.40) |
| Stroke | 0.90 (0.62-1.32) | 1.26 (0.37-4.35) |
| Transient ischemic attack | 0.85 (0.67-1.08) | 0.93 (0.55-1.57) |
| COPD | 1.04 (0.93-1.16) | 0.86 (0.68-1.09) |
| Alzheimers | 0.80 (0.59-1.07) | 1.01 (0.51-2.02) |
| Depression | 1.00 (0.92-1.09) | 0.84 (0.69-1.02) |
| Cancer | 1.06 (0.99-1.13) | 1.11 (0.97-1.27) |
| Diabetes | 1.08 (1.02-1.15) | 1.17 (1.02-1.33) |
| Kidney disease | 0.85 (0.69-1.03) | 1.05 (0.71-1.55) |
| End-stage renal disease | 0.59 (0.39-0.88) | 2.06 (0.82-5.18) |
| Flu shot | 1.19 (1.14-1.25) | 1.30 (1.19-1.42) |
| Fecal occult blood test | 1.06 (0.97-1.16) | 1.21 (1.00-1.46) |
| Mammography or PSA test | 1.15 (1.09-1.22) | 1.10 (0.98-1.23) |
aVariable was dropped from the model because patient was by definition covered during month 1.
CABG = coronary artery bypass grafting; CI = confidence interval; COPD = chronic obstructive pulmonary disease; PSA = prostate-specific antigen.