TABLE 3.
Key Health Resources and Economic Inputs
| Parameters | Value | Reference Sources |
|---|---|---|
| Health Resource Inputs | ||
| Average days of treatment | 25, Expert opiniona | |
| Oritavancin I V | 1.0 | |
| Vancomycin IV | 10.18 | |
| Linezolid IV | 13.72 | |
| Daptomycin IV | 11.06 | |
| Linezolid PO | 13.72 | |
| Outpatient mix, % | 25 | |
| Infusion center | 80.0 | |
| Home health care | 20.0 | |
| Outpatient infusion center mix, % | Expert opiniona | |
| Hospital outpatient | 90.0 | |
| Freestanding infusion clinic | 10.0 | |
| DRG mix, % | 29 | |
| DRG 602 | 8.0 | |
| DRG 603 | 72.0 | |
| DRG 856 | 2.0 | |
| DRG 857 | 4.0 | |
| DRG 858 | 1.0 | |
| DRG 862 | 4.0 | |
| DRG 863 | 9.0 | |
| Economic Inputs | ||
| DRG rate, $ | 28 | |
| DRG 602 | 7,844.37 | |
| DRG 603 | 4,512.11 | |
| DRG 856 | 25,709.68 | |
| DRG 857 | 10,961.82 | |
| DRG 858 | 7,043.12 | |
| DRG 862 | 10,151.44 | |
| DRG 863 | 5,287.04 | |
| Emergency department cost, $ | 43 | |
| ED visit (APC 0616) | 455.93 | |
| Observation unit cost, $ | 43 | |
| Observation stay, per diem (APC 8009-APC 616) | 742.98 | |
| IV drug cost (J code), $/mg | 28, Medi-Span Price Rx | |
| Vancomycin (J3370) | 2.18/500 | |
| Linezolid (J2020) | 45.66/200 | |
| Daptomycin (J0878) | 0.67/1 | |
| Oritavancin (J2407) | 2,736/1,200 | |
| Laboratory cost per test, $ | 43 | |
| Chem7 | 11.54 | |
| CBC levels | 10.61 | |
| CPK levels | 8.88 | |
| Drug trough levels | 18.49 | |
| Hepatic panel | 11.14 | |
| Other costs, $ | 43 | |
| PICC line initial placement, (APC 0621) | 849.71 | |
| X-ray to confirm placement (CPT 71010) | 24.00 | |
| Infusion center costs, $ | 43 | |
| IV infusion costs, inital hour (APC 0439) | 172.18 | |
| IV infusion costs, each subsequent hour (CPT 99602) | 29.50 | |
| IV bolus push costs, 2-minute bolus (CPT 96374) | 105.90 | |
aExpert opinion from authors Dufour, Nicolau, and Lodise.
APC = Ambulatory Payment Classification; CBC = complete blood count; CPK = creatine phosphokinase; CPT = Current Procedural Terminology; DRG = Diagnosis-Related Groups; ED = emergency department; IV = intravenous; PICC = peripherally inserted central catheter; PO = oral therapy.