| All Patients N = 10,863 | Denosumab n = 1,235 | Alendronate n = 5,458 | Ibandronate n = 1,696 | Risedronate n = 1,341 | Raloxifene n = 805 | Teriparatide n = 328 | P Valuea | |
|---|---|---|---|---|---|---|---|---|
| Mean age (SD) | 66.0 (11.4) | 66.0 (11.3) | 66.0 (11.4) | 65.5 (11.3) | 66.1 (11.6) | 66.5 (11.3) | 67.2 (10.7) | 0.153 |
| Age group, n (%) | ||||||||
| 18-54 | 1,478 (12.0) | 166 (11.8) | 742 (12.0) | 247 (12.7) | 189 (12.4) | 101 (11.2) | 34 (9.3) | 0.374 |
| 55-64 | 4,455 (41.0) | 496 (40.2) | 2,247 (41.2) | 716 (42.2) | 549 (40.9) | 323 (40.1) | 125 (38.0) | 0.714 |
| 65-74 | 2,198 (20.2) | 272 (22.0) | 1,098 (20.1) | 334 (19.7) | 258 (19.2) | 162 (20.1) | 75 (22.9) | 0.407 |
| 75-84 | 1,916 (17.6) | 205 (16.6) | 966 (17.7) | 276 (16.3) | 243 (18.1) | 149 (18.6) | 77 (23.4) | 0.045 |
| 85 + | 816 (7.5) | 97 (7.8) | 405 (7.4) | 124 (7.3) | 103 (7.7) | 70 (8.7) | 18 (5.4) | 0.530 |
| Medicare, n (%)b | 4,714 (43.4) | 539 (43.6) | 2,367 (43.4) | 701 (41.3) | 577 (43.0) | 365 (45.4) | 164 (50.1) | 0.067 |
| Health plan type, n (%) | ||||||||
| Comprehensive | 2,978 (27.4) | 338 (27.4) | 1,493 (27.4) | 442 (26.1) | 354 (26.4) | 222 (27.6) | 128 (39.1) | 0.000 |
| POS | 908 (8.4) | 105 (8.5) | 456 (8.3) | 142 (8.4) | 113 (8.4) | 65 (8.1) | 28 (8.5) | 1.000 |
| HMO | 1,458 (13.4) | 147 (11.9) | 748 (13.7) | 219 (12.9) | 185 (13.8) | 111 (13.8) | 48 (14.6) | 0.548 |
| PPO | 4,652 (42.8) | 551 (44.6) | 2,322 (42.6) | 746 (44.0) | 578 (43.1) | 344 (42.7) | 111 (33.8) | 0.017 |
| Other | 744 (6.8) | 85 (6.9) | 378 (6.9) | 122 (7.2) | 96 (7.2) | 51 (6.3) | 12 (3.8) | 0.327 |
| Unknown | 123 (1.1) | 9 (0.7) | 61 (1.1) | 25 (1.5) | 14 (1.1) | 13 (1.6) | 1 (0.3) | 0.196 |
| Geographic region, n (%) | ||||||||
| Northeast | 1,635 (15.0) | 190 (15.4) | 791 (14.5) | 248 (14.6) | 210 (15.7) | 121 (15.0) | 75 (22.8) | 0.004 |
| North Central | 2,773 (25.5) | 333 (27.0) | 1,390 (25.5) | 433 (25.5) | 334 (24.9) | 217 (27.0) | 65 (19.8) | 0.152 |
| South | 4,176 (38.4) | 457 (37.0) | 2,129 (39.0) | 658 (38.8) | 515 (38.4) | 291 (36.1) | 126 (38.4) | 0.587 |
| West | 2,256 (20.8) | 254 (20.6) | 1,136 (20.8) | 355 (21.0) | 278 (20.7) | 171 (21.2) | 62 (19.0) | 0.979 |
| Unknown | 23 (0.2) | 0 (0.0) | 12 (0.2) | 1 (0.1) | 4 (0.3) | 6 (0.7) | 0 (0.0) | 0.009 |
| Urban residence, n (%) | 9,312 (85.7) | 1,039 (84.1) | 4,690 (85.9) | 1,451 (85.6) | 1,162 (86.7) | 695 (86.4) | 274 (83.4) | 0.350 |
aP values calculated using χ2 tests for categorical variables and analysis of variance for continuous variables.
bVersus commercial.
HMO = health maintenance organization; POS = point of service; PPO = preferred provider organization; SD = standard deviation.