TABLE 4.
Cost of Biopsy Procedures in Patients with ≥ 1 Biopsy Procedure by Outpatient and Inpatient Setting
| Total Population (N = 3,579) | Previously Diagnosed Patients (n = 800) | Newly Diagnosed Patients (n = 2,779) | ||||
|---|---|---|---|---|---|---|
| Outpatient | Inpatient | Outpatient | Inpatient | Outpatient | Inpatient | |
| Total cost per patient, $ | ||||||
| Copaya | ||||||
| All patients, n | 3,031 | 973 | 709 | 183 | 2,322 | 790 |
| Mean (SD) | 60 (147) | 180 (691) | 50 (151) | 216 (742) | 63 (146) | 172 (679) |
| Median | 4 | 0 | 2 | 0 | 5 | 0 |
| Erlotinib recipients, n | 2,967 | 950 | 707 | 183 | 2,260 | 767 |
| Mean (SD) | 60 (147) | 179 (693) | 50 (151) | 216 (742) | 63 (146) | 170 (681) |
| Median | 4 | 0 | 2 | 0 | 5 | 0 |
| Crizotinib recipients, n | 64 | 23 | 2 | 0 | 62 | 23 |
| Mean (SD) | 70 (145) | 245 (610) | 4 (6) | NA | 72 (147) | 245 (610) |
| Median | 8 | 0 | 4 | NA | 11 | 0 |
| Net payb | ||||||
| All patients, n | 3,031 | 973 | 709 | 183 | 2,322 | 790 |
| Mean (SD) | 1,223 (1,899) | 8,163 (18,712) | 1,127 (1,749) | 12,409 (23,523) | 1,252 (1,942) | 7,180 (17,279) |
| Median | 534 | 331 | 491 | 473 | 542 | 322 |
| Erlotinib recipients, n | 2,967 | 950 | 707 | 183 | 2,260 | 767 |
| Mean (SD) | 1,220 (1,896) | 8,248 (18,874) | 1,130 (1,751) | 12,409 (23,523) | 1,248 (1,939) | 7,256 (17,457) |
| Median | 534 | 327 | 492 | 473 | 540 | 314 |
| Crizotinib recipients, n | 64 | 23 | 2 | 0 | 62 | 23 |
| Mean (SD) | 1,340 (2,035) | 4,651 (9,540) | 36 (50) | NA | 1,382 (2,054) | 4,651 (9,540) |
| Median | 694 | 574 | 36 | NA | 739 | 574 |
| Cost per patient by number of biopsy procedures, $ | ||||||
| 1 procedure, n | 1,911 | 861 | 431 | 166 | 1,480 | 695 |
| Copay | ||||||
| Mean (SD) | 41 (114) | 180 (713) | 29 (91) | 227 (776) | 45 (119) | 168 (698) |
| Median | 1 | 0 | 0 | 0 | 2 | 0 |
| Net pay | ||||||
| Mean (SD) | 778 (1,194) | 7,339 (16,879) | 693 (1,030) | 11,217 (22,199) | 803 (1,237) | 6,413 (15,213) |
| Median | 342 | 286 | 317 | 428 | 350 | 280 |
| 2 procedures, n | 777 | 99 | 181 | 14 | 596 | 85 |
| Copay | ||||||
| Mean (SD) | 84 (181) | 167 (457) | 79 (215) | 116 (205) | 86 (169) | 175 (487) |
| Median | 13 | 0 | 4 | 5 | 17 | 0 |
| Net pay | ||||||
| Mean (SD) | 1,581 (2,070) | 12,954 (26,350) | 1,309 (1,517) | 17,169 (29,068) | 1,664 (2,205) | 12,260 (25,996) |
| Median | 839 | 689 | 696 | 1,541 | 873 | 685 |
| 3 procedures, n | 250 | 13 | 68 | 3 | 182 | 10 |
| Copay | ||||||
| Mean (SD) | 108 (207) | 317 (679) | 90 (219) | 71 (122) | 114 (203) | 391 (765) |
| Median | 20 | 0 | 17 | 0 | 24 | 0 |
| Net pay | ||||||
| Mean (SD) | 2,530 (2,742) | 26,246 (41,013) | 2,386 (2,854) | 56,184 (32,492) | 2,584 (2,705) | 17,265 (40,246) |
| Median | 1,552 | 2,038 | 1,337 | 59,956 | 1,675 | 1,338 |
Note: Cost and SD are rounded to the nearest whole number.
a Copay corresponds to the cost in patient perspective.
b Net pay corresponds to the cost in payer perspective.
NA = not applicable; SD = standard deviation.