First-Line Treatment	Second-Line Treatment	Third-Line Treatment	N (%)	First Line (Days)		Second Line (Days)		Third Line (Days)
			Total, N = 821	Mean [SD]	Median	Mean [SD]	Median	Mean [SD]	Median
OX/IR	OX/IR + BV	Targeted biologic	275 (33.5)	114.2 [93.6]	86	195.2 [152.8]	160	188.6 [160.4]	146
OX/IR + BV	OX/IR + BV	Targeted biologic	199 (24.2)	204.7 [119.2]	195	187.4 [153.7]	143	165.0 [121.8	132
OX/IR	OX/IR + BV	NA	178 (21.7)	110.2 [79.4]	83	169.7 [119.7]	136	NA	NA
OX/IR + BV	OX/IR + BV	NA	169 (20.6)	197.8 [141.7]	168	184.4 [163.0]	145	NA	NA

BV = bevacizumab; IR = irinotecan; OX = oxaliplatin; NA = not available; SD = standard deviation.