Treatment Sequence/Line of Treatment	Mean	Standard Deviation	Distribution for PSA
Cost Per Month (2014 U.S. Dollars)
OI-OIB
Diagnosis to first line	14,585	8,306	Gamma
First line to second line	11,873	6,182	Gamma
Second line to death	13,815	10,142	Gamma
OIB-OIB
Diagnosis to first line	13,215	7,502	Gamma
First line to second line	13,632	8,060	Gamma
Second line to death	12,004	8,458	Gamma
OI-OIB-TB
Diagnosis to first line	14,097	8,406	Gamma
First line to second line	11,542	5,736	Gamma
Second line to second line end	15,438	8,289	Gamma
Third line to death	12,922	7,955	Gamma
OIB-OIB-TB
Diagnosis to first line	14,027	8,620	Gamma
First line to second line	13,530	6,313	Gamma
Second line to second line end	13,805	7,568	Gamma
Third line to death	13,742	9,646	Gamma
Health state utilities
Diagnosis	0.840	0.120	Beta
First line/second line	0.741	0.230	Beta
Third line	0.731	0.292	Beta

OI-OIB = first-line oxaliplatin/irinotecan followed by second-line oxaliplatin/irinotecan + bevacizumab; OIB-OIB = first-line oxaliplatin/irinotecan + bevacizumab followed by second-line oxaliplatin/irinotecan + bevacizumab; OI-OIB-TB = OI-OIB followed by a third-line targeted biologic; OIB-OIB-TB = OIB-OIB followed by a third-line targeted biologic; PSA = probabilistic sensitivity analysis.