TABLE 2.
Deterministic and Probabilistic Results
| Treatment | Cost, $ | QALY | Incremental Cost, $ | Incremental QALYs | Cost per QALY, $ |
|---|---|---|---|---|---|
| Base case deterministic | |||||
| Without LOE | |||||
| IM IFNβ-1a | 446,792 | 4.74 | – | – | – |
| Fingolimod | 475,740 | 4.99 | 28,948 | 0.24 | 118,434 |
| With LOE | |||||
| IM IFNβ-1a | 442,653 | 4.74 | – | – | – |
| Fingolimod | 308,570 | 4.99 | -134,084 | 0.24 | Dominant |
| Probabilistic | |||||
| Without LOE | |||||
| IM IFNβ-1a | 447,844 | 4.74 | – | – | – |
| Fingolimod | 476,486 | 4.98 | 28,642 | 0.24 | 117,614 |
| With LOE | |||||
| IM IFNβ-1a | 393,462 | 4.75 | – | – | – |
| Fingolimod | 289,547 | 4.98 | -103,915 | 0.24 | Dominant |
IM IFNβ-1a = intramuscular interferon beta-1a; LOE = loss of exclusivity; QALY = quality-adjusted life-year.