TABLE 3.
Adjusted NCQA/HEDIS Comprehensive Diabetes Care and Clinical Outcomes During Outcomes Follow-up Period
| Adjusted Effect Estimatea | Adjusted Predicted Probabilities,b % | |||||
|---|---|---|---|---|---|---|
| PWC | ||||||
| -5% | -2.5% | 0% | 2.5% | 5% | ||
| Primary analysis sample | ||||||
| A1c (as %), n = 1,520 | ||||||
| Poor control (> 9.0) | OR = 0.99 (95% CI = 0.95-1.03) P= 0.660 | NS | NS | NS | NS | NS |
| Control (< 8.0) | OR = 1.02 (95% CI = 0.99-1.05) P= 0.240 | NS | NS | NS | NS | NS |
| Control (< 7.0) | OR = 1.05 (95% CI = 1.03-1.09) P < 0.001 | 58.8 | 55.9 | 52.8 | 49.8 | 46.7 |
| Control (< 6.5) | OR = 1.08 (95% CI = 1.05-1.11) P < 0.001 | 43.1 | 39.0 | 35.1 | 31.3 | 27.8 |
| Blood pressure (mm Hg), n = 1,520 | ||||||
| Control (< 130/80 mm Hg) | OR = 1.01 (95% CI = 0.99-1.04) P= 0.380 | NS | NS | NS | NS | NS |
| Control (< 140/90 mm Hg) | OR = 1.00 (95% CI = 0.98-1.03) P= 0.700 | NS | NS | NS | NS | NS |
| LDL-C (mg/dL), n = 756c | ||||||
| Control (< 100 mg/dL) | OR = 1.02 (95% CI = 0.99-1.06) P= 0.210 | NS | NS | NS | NS | NS |
| Subgroup sample d | ||||||
| A1c (as %), n = 780 | ||||||
| Poor control (> 9.0) | OR = 0.96 (95% CI = 0.90-1.03) P= 0.250 | NS | NS | NS | NS | NS |
| Control (< 8.0) | OR = 1.08 (95% CI = 1.02-1.14) P= 0.010 | 86.6 | 84.8 | 82.8 | 80.7 | 78.3 |
| Control (< 7.0) | OR = 1.11 (95% CI = 1.06-1.15) P < 0.001 | 63.2 | 57.9 | 52.5 | 47.1 | 41.7 |
| Control (< 6.5) | OR = 1.09 (95% CI = 1.04-1.12) P < 0.001 | 43.9 | 39.8 | 35.8 | 32.0 | 28.3 |
| Blood pressure (mm Hg), n = 780 | ||||||
| Control (< 130/80 mm Hg) | OR = 0.98 (95% CI = 0.94-1.02) P= 0.410 | NS | NS | NS | NS | NS |
| Control (< 140/90 mm Hg) | OR = 0.97 (95% CI = 0.94-1.01) P= 0.144 | NS | NS | NS | NS | NS |
| LDL-C (mg/dL), n = 403c | ||||||
| Control (< 100 mg/dL) | OR = 1.03 (95% CI = 0.97-1.09) P= 0.287 | NS | NS | NS | NS | NS |
a Association between 1 percentage point decrease in PWC and outcome.
b Adjusted predicted probabilities of attaining A1c goals calculated for outcomes with which the PWC was significantly associated.
c Analyses conducted on a subset of patients for whom LDL-C data were available.
d Sample restricted to patients with BMI ≥ 30 and no evidence of previous cardiovascular disease.
Alc = hemoglobin A1c; BMI = body mass index; CI = confidence interval; LDL-C = low-density lipoprotein cholesterol; NCQA/HEDIS = National Committee for Quality
Assurance/Healthcare Effectiveness Data and Information Set; NS = not significant; OR = odds ratio; PWC = percentage weight change.