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. 2016 May;22(5):10.18553/jmcp.2016.22.5.526. doi: 10.18553/jmcp.2016.22.5.526

TABLE 2.

Unadjusted Changes in Adherence by Treatment Group

Oral Antidiabetics Antihypertensives Statins
Intervention n = 1,277 Control n = 4,144 P Value Intervention n = 4,787 Control n = 14,733 P Value Intervention n = 4,382 Control n = 14,862 P Value
PDC, mean
Preperiod,a % 87.6 89.5 88.5 90.8 87.2 88.9
Postperiod,b % 89.1 90.3 89.9 90.2 88.5 88.4
Difference (preperiod to postperiod)c 1.5 0.8 0.206 1.4 -0.6 < 0.001 1.3 -0.5 < 0.001
Difference-in-differenced +0.7 +2.0 +1.8
PDC ≥ 80, %
Preperiod,a % 78.6 80.3 80.2 85.2 78.1 81.1
Postperiod,b % 81.7 83.6 82.8 83.9 80.9 80.3
Difference (preperiod to postperiod)c 3.1 3.3 0.178 2.6 -1.3 < 0.001 2.8 -0.8 0.090
Difference-in-differenced -0.2 +3.9 +3.6

Note: T-tests used to assess statistical difference between treatment groups for the continuous PDC outcome. Chi-square tests used to assess statistical associations for the categorical PDC ≥ 80 outcome.

a Preperiod = April 2012 to March 2013.

b Postperiod = April 2013 to March 2014.

c Difference = preperiod to postperiod.

d Difference-in-difference = difference (intervention)–difference (control).

PDC = proportion of days covered.