TABLE 5.

Intervention Effects on Adherence to Statins

Variable	PDC (Continuous)			PDC ≥ 80% (Binary)
							95% CI
	Coefficient	SE	P Value	Coefficient	SE	OR	Upper	Lower	P Value
Female (reference: male)	-0.008	0.002	< 0.0001	-0.130	0.031	0.878	0.826	0.933	< 0.0001
Age group, years (reference: < 55 years)	1.000	1.000
55-64	0.026	0.007	0.000	0.273	0.101	1.313	1.077	1.601	0.0071
65-74	0.029	0.006	< 0.0001	0.294	0.091	1.341	1.122	1.604	0.0013
75+	0.030	0.006	< 0.0001	0.305	0.092	1.356	1.133	1.623	0.0009
Comorbidity count (reference: < 3)
3-4	0.000	0.002	0.780	0.029	0.031	1.030	0.968	1.095	0.3519
5-6	-0.005	0.002	0.033	-0.051	0.041	0.951	0.877	1.030	0.218
7-8	-0.006	0.004	0.131	-0.087	0.064	0.917	0.809	1.039	0.1745
9+	-0.010	0.007	0.168	-0.221	0.106	0.802	0.652	0.987	0.037
New to therapy	-0.014	0.002	< 0.0001	-0.405	0.039	0.667	0.618	0.720	< 0.0001
90-day refill	0.059	0.002	< 0.0001	0.644	0.033	1.904	1.784	2.031	< 0.0001
Number of target medication classes (reference: 1)
2	0.008	0.002	< 0.0001	0.100	0.032	1.105	1.039	1.176	0.0016
3	0.014	0.003	< 0.0001	0.177	0.046	1.194	1.091	1.305	0.0001
Low-income subsidy	-0.001	0.002	0.6310	-0.054	0.040	0.947	0.875	1.025	0.1785
Time (reference: preperioda)	-0.007	0.001	< 0.0001	-0.114	0.025	0.893	0.849	0.938	< 0.0001
Group (reference: control)	-0.012	0.003	< 0.0001	-0.120	0.043	0.887	0.815	0.965	0.0053
Group × Time interactionb	0.018	0.003	< 0.0001	0.221	0.049	1.247	1.132	1.374	< 0.0001

Note: Generalized linear models used to assess statistical difference between treatment groups for continuous PDC outcomes. Logistic regression used for PDC ≥ 80% binary outcome.

^a Preperiod = April 2012 to March 2013; postperiod = April 2013 to March 2014.

^b Group × Time interaction variable is difference-in-difference estimator.

CI = confidence interval; OR = odds ratio; PDC = proportion of days covered; SE = standard error.