TABLE 3.
Weighted All-Cause and PsO-Related Per Patient Per Month Health Care Costs, IXE Versus SEC and IXE Versus ADA
| Cost Per Patient Per Month | IXE | SEC | P Value, Mean | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | Median (Rangea) | Mean (SD) | Median (Rangea) | ||||||
| All-cause costs, USD (SD) | |||||||||
| Total health care | 7,313 (4,142) | 6,680 (5,488-7,915) | 6,477 (4,144) | 5,827 (4,624-7,107) | 0.002 | ||||
| Inpatient admissions | 247 (1,426) | 0 (0-0) | 241 (1,280) | 0 (0-0) | 0.942 | ||||
| Outpatient services | 611 (1,997) | 166 (78-469) | 614 (1,831) | 211 (79-559) | 0.981 | ||||
| Outpatient pharmacy | 6,455 (3,226) | 6,301 (5,015-7,190) | 5,621 (3,408) | 5,417 (4,213-6,244) | < 0.001 | ||||
| PsO-related costs, USD (SD) | |||||||||
| Total health care | 6,303 (3,191) | 6,252 (4,994-7,122) | 5,437 (3,367) | 5,265 (4,080-6,071) | < 0.001 | ||||
| Inpatient admissions | 0 (0) | 0 (0-0) | 0 (0) | 0 (0-0) | N/A | ||||
| Outpatient services | 40 (137) | 21 (11-35) | 54 (251) | 22 (11-36) | 0.221 | ||||
| Outpatient pharmacy | 6,263 (3,184) | 6,206 (4,960-7,098) | 5,382 (3,370) | 5,228 (4,032-6,034) | < 0.001 | ||||
| Index drug costs, USD (SD) | 5,613 (2,495) | 5,826 (4,194-6,729) | 4,626 (2,823) | 4,723 (3,065-5,670) | < 0.001 | ||||
| Cost Per Patient Per Month | IXE | ADA | P Value, Mean | ||||||
| Mean (SD) | Median (Rangea) | Mean (SD) | Median (Rangea) | ||||||
| All-cause costs, USD (SD) | |||||||||
| Total health care | 6,535 (3,051) | 6,206 (5,154-7,322) | 5,557 (4,677) | 4,914 (3,605-5,943) | 0.026 | ||||
| Inpatient admissions | 186 (986) | 0 (0-0) | 181 (1,651) | 0 (0-0) | 0.934 | ||||
| Outpatient services | 418 (1,003) | 154 (63-393) | 467 (1,319) | 172 (68-435) | 0.366 | ||||
| Outpatient pharmacy | 5,930 (2,646) | 6,024 (4,730-6,744) | 4,909 (4,167) | 4,513 (3,226-5,436) | 0.019 | ||||
| PsO-related costs, USD (SD) | |||||||||
| Total health care | 5,792 (2,593) | 5,902 (4,616-6,622) | 4,754 (4,015) | 4,400 (3,138-5,316) | 0.017 | ||||
| Inpatient admissions | 6 (139) | 0 (0-0) | 2 (65) | 0 (0-0) | 0.502 | ||||
| Outpatient services | 34 (96) | 20 (10-33) | 57 (776) | 19 (10-33) | 0.135 | ||||
| Outpatient pharmacy | 5,751 (2,584) | 5,869 (4,597-6,581) | 4,695 (3,965) | 4,361 (3,093-5,271) | 0.015 | ||||
| Index drug costs, USD (SD) | 5,328 (2,382) | 5,555 (3,924-6,412) | 3,588 (1,884) | 3,716 (2,180-4,842) | < 0.001 | ||||
aReported range is the 25th percentile and the 75th percentile.
ADA = adalimumab; IXE = ixekizumab; N/A = not applicable; PsO = psoriasis; SEC = secukinumab; SD = standard deviation.