TABLE 3.

Treatment Differences in Time Periods by Medication Type, 2000-2009, Percentage of Constipation and/or IBS Visits with Prescribed Medication (Range)

Age Range, Years	Weighted Number of Visits (Millions)	Time Period	Lubiprostone	Stimulant Laxative	Stool Softener	Prokinetic	Lubricant	Hyperosmolar Agent	Saline Laxative	Sodium Phosphate	Tegaserod	Fiber, Any	Combination Therapya
< 18	1.2	2000-2004	—	10 (4-23)	6 (2-15)	2 (1-8)	17 (9-32)b	74 (58-85)c	6 (2-17)b	—	—	3 (1-13)	17 (8-31)
		2005-2009	—	8 (4-17)	3 (1-8)	—	2 (0-7)b	90 (82-95)c	0 (0-1)b	—	—	3 (1-9)	6 (2-14)
18-44	9.4	2000-2004	—	3 (1-11)c	21 (9-42)	4 (1-24)	2 (0-8)	34 (19-53)	3 (1-12)	0 (0-2)	22 (9-42)	25 (14-40)	15 (5-38)
		2005-2009	9 (3-21)	15 (7-28)c	13 (6-27)	6 (1-23)	4 (1-23)	36 (23-51)	0 (0-2)	—	8 (2-30)	24 (12-41)	19 (10-33)
45-64	10.5	2000-2004	—	13 (4-32)c	9 (3-24)	9 (3-24)	—	44 (30-60)	6 (1-19)	—	11 (4-28)	14 (6-30)	4 (1-19)
		2005-2009	6 (2-17)	1 (0-5)c	8 (3-16)	3 (1-14)	—	55 (39-69)	1 (0-4)	—	13 (6-26)	15 (7-29)	4 (1-10)
≥ 65	2.8	2000-2004	—	9 (3-20)	20 (10-37)	2 (1-8)	3 (1-12)	39 (24-56)	10 (4-22)c	3 (1-13)	14 (5-30)c	23 (13-38)	23 (12-37)
		2005-2009	6 (2-15)	8 (4-16)	21 (12-33)	4 (1-15)	0 (0-2)	46 (34-58)	2 (0-7)c	—	2 (1-8)c	29 (19-43)	18 (10-29)
All visits	28.2	2000-2004	—	8 (5-14)	13 (8-21)	3 (1-9)	8 (4-13)b	52 (42-61)	6 (3-11)b	1 (0-3)	10 (6-17)	15 (10-21)	16 (10-24)
		2005-2009	5 (3-9)	8 (5-12)	11 (8-16)	3 (1-8)	2 (0-5)b	58 (50-65)	1 (0-2)b	—	5 (3-10)	18 (13-25)	12 (8-17)

Note: empty cells indicate zero occurances in the sample

^aRepresents patients prescribed at least 1 medication and nonpharmacologic treatment.

^bP < 0.01.

^cP < 0.05 for 2000-2004 versus 2005-2009.

IBS = irritable bowel syndrome.