TABLE 5.
Treatment Differences in Time Periods by Medication Type, 2000-2009, Percentage of All-Cause Constipation Visits with Prescribed Medication (Range)
| Age Range, Years | Weighted Number of Visits (Millions) | Time Period | Lubiprostone | Stimulant Laxative | Stool Softener | Prokinetic | Lubricant | Hyperosmolar Agent | Saline Laxative | Sodium Phosphate | Tegaserod | Fiber, Any | Combination Therapya |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| < 18 | 18.0 | 2000-2004 | — | 10 (4-23) | 6 (2-15) | 2 (1-8) | 17 (9-32)b | 74 (58-85)c | 6 (2-17)b | — | — | 3 (1-13) | 17 (8-31) |
| 2005-2009 | — | 8 (4-18) | 3 (1-8) | — | 2 (0-7)b | 90 (82-95)c | 0 (0-1)b | — | — | 3 (1-9) | 6 (2-14) | ||
| 18-44 | 11.9 | 2000-2004 | — | 3 (1-14)c | 26 (12-49) | 3 (0-16) | 3 (1-10) | 38 (20-59) | 4 (1-14) | 0 (0-2) | 24 (10-48) | 17 (8-33) | 18 (6-44) |
| 2005-2009 | 5 (1-16) | 17 (9-32)c | 15 (7-31) | 5 (1-28) | 5 (1-26) | 41 (27-57) | 0 (0-3) | — | 8 (1-35) | 21 (9-40) | 22 (12-37) | ||
| 45-64 | 13.3 | 2000-2004 | — | 15 (4-41)c | 8 (2-26) | 6 (1-27) | — | 55 (35-73) | 8 (2-27)c | — | 12 (3-35) | 3 (1-12) | 6 (1-27) |
| 2005-2009 | 7 (2-20) | 1 (0-6)c | 9 (4-19) | — | — | 59 (42-74) | 1 (0-5)c | — | 11 (4-24) | 15 (6-31) | 4 (1-12) | ||
| ≥ 65 | 20.3 | 2000-2004 | — | 10 (4-23) | 24 (11-43) | 3 (1-10) | 4 (1-15) | 48 (31-65) | 12 (5-26)c | 4 (1-15) | 8 (2-24) | 16 (8-30) | 27 (15-44) |
| 2005-2009 | 6 (2-17) | 9 (4-17) | 23 (14-35) | 1 (0-4) | 0 (0-1) | 49 (37-62) | 2 (0-7)c | — | 2 (1-8) | 24 (15-38) | 19 (11-32) | ||
| All visits | 63.4 | 2000-2004 | — | 9 (5-16) | 15 (9-23) | 3 (1-7) | 9 (5-15)c | 58 (47-68) | 7 (4-13)d | 1 (0-4) | 8 (4-16) | 9 (6-15) | 18 (12-27) |
| 2005-2009 | 4 (2-8) | 9 (6-13) | 12 (9-17) | 1 (0-6) | 2 (1-5)c | 62 (54-69) | 1 (0-2)d | — | 4 (2-9) | 15 (10-22) | 13 (9-18) |
Note: empty cells indicate zero occurances in the sample
aRepresents patients prescribed at least 1 medication and nonpharmacologic treatment..
bP < 0.01.
cP < 0.05 for 2000-2004 versus 2005-2009.
dP < 0.001.