TABLE 3.
A1c Results for Patients with Recorded A1c During 6-Month Baseline Period and Last 3 Months of Post-Index Year
| Persistent with MDI (n = 83) | Nonpersistent with MDI (n = 248) | P Valuea | |
|---|---|---|---|
| Baseline A1c | |||
| A1c (%), mean (SD) | 9.67 (1.9) | 9.60 (2.1) | 0.631 |
| A1c (%), median (range) | 9.2 (6.5-17.2) | 9.2 (5.9-18.2) | |
| Post-index A1c | |||
| A1c (%), mean (SD) | 8.38 (1.5) | 8.84 (1.8) | 0.054 |
| A1c (%), median (range) | 8.0 (5.6-12.6) | 8.4 (5.2-14.9) | |
| Change from baseline | |||
| Mean (SD) change in A1c, % | -1.29 (2.0)b | -0.76 (2.1)b | 0.006 |
| Median (range) change in A1c, % | -1.0 (-8.9 to 5.6) | -0.45 (-9.4 to 5.8) | |
| Treatment success, n (%) | |||
| A1c decrease ≥ 1% from baseline | 44 (53.0) | 94 (37.9) | |
| A1c baseline > 7% & post-index ≤ 7% | 11 (13.3) | 19 (7.7) | |
| Either definition of treatment success | 46 (55.4) | 97 (39.1) | 0.009 |
aThe chi-square test was used to compare categorical variables, and the Wilcoxon rank sum was used to compare continuous variables.
bP <0.0001 (Wilcoxon signed rank test) for within-cohort change from mean baseline A1c to mean A1c value during the past 3 months of the post-index year. A1c = hemoglobin A1c; MDI = multiple daily insulin injections; SD = standard deviation.