Supplementary Table 2. The expression of all anoikis-related genes.
| Gene | ConMean | TreatMean | logFC | p value | fdr |
|---|---|---|---|---|---|
| BRMS1 | 18.31334 | 40.09548 | 1.130545 | 8.39E-18 | 8.98E-17 |
| PTK2 | 4.637303 | 9.191043 | 0.986943 | 7.18E-17 | 6.70E-16 |
| BCL2L11 | 3.281152 | 5.427075 | 0.725972 | 9.47E-09 | 2.35E-08 |
| SRC | 9.476183 | 15.98159 | 0.754033 | 2.41E-11 | 7.98E-11 |
| CEACAM6 | 120.5597 | 33.36922 | −1.85316 | 4.15E-13 | 1.84E-12 |
| CAV1 | 24.22758 | 98.38569 | 2.021798 | 1.02E-12 | 4.44E-12 |
| AKT1 | 8.906661 | 13.19592 | 0.567135 | 5.39E-12 | 2.04E-11 |
| ITGB1 | 29.83564 | 57.29262 | 0.941313 | 1.12E-08 | 2.74E-08 |
| CEACAM5 | 145.188 | 28.17943 | −2.36521 | 1.58E-08 | 3.77E-08 |
| EGFR | 15.54844 | 39.43583 | 1.342737 | 5.40E-07 | 1.06E-06 |
| CASP8 | 2.141759 | 3.781403 | 0.820125 | 2.05E-11 | 6.97E-11 |
| PTRH2 | 2.828445 | 4.589057 | 0.698189 | 4.66E-10 | 1.35E-09 |
| STAT3 | 35.27708 | 36.36855 | 0.043961 | 0.654895 | 0.673394 |
| SIK1 | 1.175423 | 1.026727 | −0.19513 | 0.843183 | 0.85019 |
| TLE1 | 5.616875 | 7.83431 | 0.480038 | 2.46E-07 | 5.08E-07 |
| DAPK2 | 1.002264 | 0.694241 | −0.52975 | 0.006703 | 0.009071 |
| CTNNB1 | 50.68536 | 51.67402 | 0.02787 | 0.913102 | 0.915617 |
| ZNF304 | 2.083512 | 2.433126 | 0.223793 | 0.029328 | 0.037326 |
| BMF | 1.414171 | 2.970118 | 1.070564 | 1.09E-09 | 2.98E-09 |
| MAPK1 | 11.04435 | 13.72781 | 0.313794 | 9.04E-05 | 0.000147 |
| ITGA5 | 4.903082 | 28.72014 | 2.550302 | 9.95E-21 | 2.01E-19 |
| MCL1 | 108.2345 | 114.52 | 0.081438 | 0.291929 | 0.32397 |
| BCL2L1 | 27.23383 | 30.72361 | 0.173948 | 0.15571 | 0.181081 |
| CASP3 | 11.35766 | 14.67126 | 0.369327 | 0.000314 | 0.000479 |
| BAD | 16.34459 | 24.39265 | 0.577633 | 7.51E-07 | 1.43E-06 |
| PIK3CA | 2.380573 | 4.340237 | 0.866465 | 1.41E-11 | 4.90E-11 |
| PAK1 | 8.587547 | 15.70234 | 0.870662 | 1.94E-10 | 5.75E-10 |
| ITGAV | 11.75486 | 28.89517 | 1.297571 | 5.61E-14 | 3.10E-13 |
| FN1 | 14.90543 | 134.6144 | 3.174923 | 4.79E-16 | 3.87E-15 |
| MAPK3 | 26.35448 | 17.3991 | −0.59904 | 1.37E-10 | 4.08E-10 |
| PTGS2 | 2.972568 | 10.72968 | 1.851825 | 0.000572 | 0.000853 |
| BAX | 12.44263 | 23.10898 | 0.893162 | 1.36E-16 | 1.21E-15 |
| BCAR1 | 7.399878 | 11.62259 | 0.651358 | 9.21E-10 | 2.54E-09 |
| PTEN | 6.633318 | 7.598861 | 0.196052 | 0.010535 | 0.013995 |
| ERBB2 | 25.54295 | 20.47268 | −0.31922 | 3.47E-10 | 1.01E-09 |
| PDK4 | 39.65115 | 2.901449 | −3.77252 | 1.41E-15 | 1.01E-14 |
| ANGPTL4 | 15.65958 | 19.98927 | 0.35218 | 0.220457 | 0.249212 |
| CYCS | 31.68959 | 34.92588 | 0.140287 | 0.277131 | 0.308488 |
| ANKRD13C | 4.193882 | 4.643341 | 0.146877 | 0.031307 | 0.039707 |
| BRAF | 1.952846 | 2.164484 | 0.148445 | 0.329477 | 0.362325 |
| ANXA5 | 51.35229 | 94.19229 | 0.87518 | 2.42E-13 | 1.14E-12 |
| MTOR | 5.518004 | 6.730803 | 0.286632 | 0.003123 | 0.004355 |
| BIRC5 | 5.051176 | 20.54713 | 2.024246 | 2.54E-24 | 2.32E-22 |
| TIMP1 | 95.74281 | 128.9646 | 0.429739 | 5.44E-05 | 9.09E-05 |
| ITGA2 | 12.58255 | 18.35073 | 0.544413 | 0.000313 | 0.000479 |
| CSPG4 | 4.163772 | 18.8308 | 2.177131 | 2.09E-10 | 6.13E-10 |
| BSG | 101.312 | 166.4619 | 0.716388 | 6.24E-14 | 3.39E-13 |
| AKT2 | 7.676326 | 7.884142 | 0.038538 | 0.986085 | 0.986085 |
| STK11 | 5.982203 | 7.778649 | 0.378843 | 1.40E-06 | 2.61E-06 |
| IGF1 | 0.25138 | 0.123164 | −1.02929 | 3.06E-06 | 5.60E-06 |
| IGF1R | 4.979949 | 9.995816 | 1.005193 | 7.48E-12 | 2.70E-11 |
| ITGA6 | 32.65177 | 143.8335 | 2.139167 | 3.79E-19 | 5.52E-18 |
| ILK | 2.289875 | 3.004701 | 0.391952 | 3.62E-05 | 6.10E-05 |
| CFLAR | 4.929788 | 4.616782 | −0.09464 | 0.057301 | 0.070465 |
| RHOA | 170.6279 | 159.1221 | −0.10072 | 0.005931 | 0.008085 |
| HIF1A | 32.81322 | 67.25712 | 1.03541 | 2.96E-12 | 1.17E-11 |
| DAP3 | 14.03513 | 19.78896 | 0.495653 | 5.35E-12 | 2.04E-11 |
| MYBBP1A | 10.28701 | 14.68264 | 0.513288 | 1.32E-07 | 2.80E-07 |
| ITGA3 | 15.59001 | 57.98995 | 1.895181 | 7.21E-16 | 5.35E-15 |
| PTK2B | 5.230626 | 8.19616 | 0.647964 | 4.48E-07 | 9.06E-07 |
| CCND1 | 40.29128 | 64.57769 | 0.680568 | 0.570333 | 0.598275 |
| CTTN | 34.58309 | 81.80493 | 1.242121 | 4.29E-05 | 7.19E-05 |
| CALR | 234.1102 | 421.6166 | 0.848744 | 8.40E-21 | 1.80E-19 |
| CHEK2 | 1.75091 | 4.046747 | 1.208658 | 3.21E-15 | 2.12E-14 |
| SKP2 | 4.439742 | 10.44456 | 1.234203 | 1.69E-15 | 1.14E-14 |
| E2F1 | 2.056468 | 10.93776 | 2.411077 | 1.12E-24 | 1.36E-22 |
| EGF | 1.406144 | 0.353105 | −1.99357 | 1.03E-05 | 1.82E-05 |
| PIK3CG | 0.423677 | 0.703268 | 0.731109 | 0.118015 | 0.139472 |
| ITGB4 | 48.31807 | 140.246 | 1.537325 | 3.69E-18 | 4.20E-17 |
| PIK3R1 | 8.780768 | 4.247492 | −1.04774 | 6.58E-07 | 1.27E-06 |
| MAP2K1 | 13.94483 | 19.01097 | 0.447102 | 6.72E-09 | 1.72E-08 |
| CXCL12 | 15.01197 | 5.444742 | −1.46318 | 4.72E-07 | 9.50E-07 |
| LGALS3 | 125.5295 | 88.99508 | −0.49623 | 3.50E-05 | 5.95E-05 |
| BAK1 | 14.99677 | 30.67254 | 1.032296 | 1.71E-13 | 8.55E-13 |
| ABHD4 | 9.74255 | 12.269 | 0.332646 | 0.233094 | 0.261871 |
| CD44 | 58.7771 | 105.6647 | 0.846168 | 4.83E-11 | 1.50E-10 |
| ITGA4 | 0.533643 | 1.252057 | 1.230354 | 6.23E-05 | 0.000103 |
| FADD | 3.871827 | 16.37527 | 2.080432 | 3.41E-21 | 8.88E-20 |
| TGFB1 | 12.69138 | 45.45074 | 1.840455 | 3.46E-25 | 1.26E-22 |
| HMCN1 | 0.867611 | 1.299774 | 0.58314 | 0.668624 | 0.685575 |
| MMP2 | 38.69276 | 78.27592 | 1.016505 | 7.98E-09 | 2.00E-08 |
| CEBPB | 29.05665 | 46.08272 | 0.665357 | 4.36E-08 | 9.85E-08 |
| CDKN3 | 2.725998 | 10.06447 | 1.884414 | 9.26E-24 | 5.62E-22 |
| CBL | 2.274933 | 3.687269 | 0.696728 | 3.01E-08 | 6.90E-08 |
| CASP9 | 2.789836 | 2.474241 | −0.17319 | 0.025822 | 0.03333 |
| SFN | 2034.71 | 2527.442 | 0.312855 | 0.108271 | 0.12964 |
| MTDH | 16.87518 | 27.05149 | 0.680805 | 1.33E-13 | 6.91E-13 |
| TNFRSF10B | 7.036808 | 15.80843 | 1.167701 | 4.24E-15 | 2.66E-14 |
| CXCL8 | 13.85515 | 50.9419 | 1.878431 | 1.02E-07 | 2.19E-07 |
| AR | 0.841429 | 0.279 | −1.59258 | 2.16E-13 | 1.04E-12 |
| CDKN2A | 1.010931 | 12.66919 | 3.647567 | 8.32E-05 | 0.000136 |
| PIK3CB | 4.650559 | 5.635174 | 0.277056 | 0.102067 | 0.122615 |
| CPT1A | 9.363545 | 13.53872 | 0.531965 | 0.126443 | 0.148469 |
| MAPK8 | 2.260326 | 2.877347 | 0.348209 | 0.000116 | 0.000185 |
| CLDN1 | 53.72277 | 116.1745 | 1.112688 | 0.000155 | 0.000242 |
| CDKN1A | 91.1972 | 114.5772 | 0.329258 | 0.006928 | 0.00934 |
| ATF4 | 103.0126 | 113.7047 | 0.142471 | 0.173561 | 0.199294 |
| KLF12 | 0.641811 | 1.081368 | 0.752639 | 0.00024 | 0.00037 |
| NTRK1 | 0.058011 | 0.241851 | 2.059711 | 4.82E-14 | 2.70E-13 |
| MYC | 73.5427 | 72.22842 | −0.02602 | 0.473958 | 0.505926 |
| PLAU | 17.17849 | 110.7916 | 2.689173 | 9.82E-22 | 2.75E-20 |
| SMAD4 | 3.646231 | 3.539153 | −0.043 | 0.160407 | 0.185949 |
| MUC1 | 31.19732 | 15.43909 | −1.01483 | 0.001558 | 0.002224 |
| PLK1 | 3.524893 | 13.33401 | 1.919459 | 8.79E-23 | 2.86E-21 |
| PLAUR | 6.597745 | 16.0868 | 1.285833 | 2.62E-13 | 1.22E-12 |
| LGALS1 | 109.0298 | 368.78 | 1.758038 | 1.07E-14 | 6.52E-14 |
| PYCARD | 17.38101 | 31.98672 | 0.879961 | 5.27E-08 | 1.16E-07 |
| KRAS | 6.60387 | 7.920921 | 0.262357 | 0.170122 | 0.196585 |
| BID | 3.94089 | 9.340369 | 1.244958 | 6.64E-16 | 5.04E-15 |
| HRAS | 31.41219 | 45.08741 | 0.5214 | 3.57E-05 | 6.05E-05 |
| CDK11B | 6.215619 | 7.878761 | 0.342071 | 2.98E-07 | 6.08E-07 |
| CDK11A | 0.595995 | 1.011396 | 0.762976 | 5.78E-10 | 1.63E-09 |
| XIAP | 6.030716 | 7.499299 | 0.314426 | 0.000936 | 0.001373 |
| PPARG | 2.888424 | 0.75499 | −1.93575 | 2.08E-17 | 2.10E-16 |
| IL6 | 14.19213 | 5.87052 | −1.27353 | 0.059691 | 0.072912 |
| CCR7 | 1.526339 | 2.867334 | 0.909634 | 0.006197 | 0.008417 |
| RAC1 | 105.512 | 131.6608 | 0.319419 | 0.000512 | 0.000769 |
| NOTCH1 | 10.07847 | 12.16974 | 0.272022 | 0.109591 | 0.130791 |
| RHOG | 32.81732 | 42.27302 | 0.36528 | 6.36E-06 | 1.14E-05 |
| CCAR2 | 9.937999 | 12.43619 | 0.323517 | 0.007075 | 0.009468 |
| NQO1 | 32.52281 | 46.23674 | 0.507588 | 0.400556 | 0.436534 |
| BIRC3 | 4.087472 | 8.081941 | 0.983493 | 0.114541 | 0.135807 |
| MMP13 | 0.847039 | 70.49821 | 6.379014 | 1.19E-20 | 2.28E-19 |
| MTA1 | 4.318061 | 7.704283 | 0.835277 | 1.05E-13 | 5.55E-13 |
| MYO5A | 2.868487 | 6.507435 | 1.181799 | 6.24E-12 | 2.33E-11 |
| EDA2R | 0.651582 | 0.319245 | −1.02928 | 2.71E-06 | 4.99E-06 |
| MMP9 | 4.682507 | 79.76467 | 4.090397 | 3.49E-23 | 1.59E-21 |
| ABL1 | 11.62789 | 14.91791 | 0.359456 | 6.23E-05 | 0.000103 |
| MAPK11 | 3.662574 | 6.672163 | 0.865297 | 2.38E-11 | 7.94E-11 |
| PTHLH | 5.480407 | 63.67381 | 3.538345 | 1.19E-18 | 1.61E-17 |
| PDGFB | 3.104907 | 6.560776 | 1.079317 | 1.30E-09 | 3.52E-09 |
| GLI2 | 0.643801 | 1.899178 | 1.560689 | 0.021299 | 0.027689 |
| EZH2 | 3.171713 | 6.638469 | 1.065588 | 1.20E-08 | 2.92E-08 |
| CXCR4 | 9.222526 | 19.14025 | 1.053376 | 0.000385 | 0.000581 |
| RIPK1 | 9.502309 | 10.97815 | 0.208285 | 0.017865 | 0.023476 |
| HMGA1 | 104.1887 | 181.4746 | 0.800569 | 2.40E-08 | 5.56E-08 |
| TNFSF10 | 37.08434 | 85.98443 | 1.213266 | 3.80E-08 | 8.65E-08 |
| SIK2 | 5.116516 | 3.808725 | −0.42585 | 0.000353 | 0.000535 |
| ANGPTL2 | 13.82291 | 17.5634 | 0.345511 | 0.18255 | 0.208956 |
| S100A4 | 73.64563 | 71.20226 | −0.04868 | 0.611618 | 0.632469 |
| ETV4 | 3.926077 | 8.900659 | 1.180824 | 5.10E-07 | 1.02E-06 |
| NTF3 | 0.90704 | 0.389738 | −1.21866 | 3.23E-13 | 1.45E-12 |
| HTRA1 | 30.30233 | 81.21947 | 1.422397 | 2.78E-11 | 8.96E-11 |
| LATS1 | 3.250592 | 4.076164 | 0.32651 | 0.001668 | 0.002372 |
| CEACAM3 | 0.165774 | 0.151992 | −0.12522 | 0.110256 | 0.131154 |
| EIF2AK3 | 4.39196 | 4.115332 | −0.09386 | 0.525864 | 0.558059 |
| LAMC2 | 16.7289 | 230.3645 | 3.783504 | 3.42E-23 | 1.59E-21 |
| LAMB3 | 53.5958 | 223.739 | 2.061625 | 1.29E-18 | 1.65E-17 |
| LAMA3 | 5.18223 | 40.17894 | 2.954794 | 1.50E-19 | 2.38E-18 |
| CDH2 | 0.27806 | 1.153357 | 2.052374 | 0.007012 | 0.009418 |
| CSNK2A1 | 13.76656 | 18.14122 | 0.398103 | 7.01E-09 | 1.78E-08 |
| EDIL3 | 1.82772 | 5.408707 | 1.565239 | 2.91E-05 | 4.98E-05 |
| ZEB2 | 0.875709 | 1.047074 | 0.25784 | 0.035613 | 0.044503 |
| TLN1 | 24.25519 | 36.83547 | 0.602802 | 0.000152 | 0.000239 |
| EPHA2 | 73.39707 | 43.16752 | −0.76578 | 0.000195 | 0.000304 |
| SIRT3 | 2.986587 | 3.072916 | 0.04111 | 0.408986 | 0.441754 |
| CEMIP | 5.045043 | 5.995218 | 0.248946 | 0.053249 | 0.065704 |
| CLU | 111.1711 | 25.97697 | −2.09748 | 5.88E-16 | 4.55E-15 |
| SPINK1 | 0.044008 | 0.413958 | 3.233664 | 8.26E-10 | 2.30E-09 |
| CPEB2 | 4.878915 | 4.142881 | −0.23593 | 0.032019 | 0.040468 |
| NAT1 | 1.548264 | 1.23559 | −0.32545 | 0.441969 | 0.473166 |
| TSG101 | 17.30285 | 17.32565 | 0.001899 | 0.792857 | 0.803899 |
| SERPINA1 | 3.733868 | 9.802049 | 1.392412 | 3.01E-07 | 6.12E-07 |
| AKT3 | 1.090395 | 2.369531 | 1.11975 | 5.96E-07 | 1.16E-06 |
| RELA | 17.2217 | 21.74284 | 0.336313 | 7.19E-07 | 1.38E-06 |
| PRKCA | 1.0391 | 1.818962 | 0.80778 | 1.04E-05 | 1.83E-05 |
| TNFRSF1A | 36.22132 | 48.37269 | 0.417354 | 4.64E-09 | 1.22E-08 |
| FASLG | 0.323249 | 0.723503 | 1.162353 | 0.024714 | 0.032015 |
| AFP | 0.007351 | 0.039632 | 2.430618 | 6.42E-05 | 0.000106 |
| SATB1 | 2.311661 | 1.122729 | −1.04192 | 8.91E-11 | 2.70E-10 |
| EEF1A1 | 770.3657 | 582.4162 | −0.40349 | 2.42E-07 | 5.03E-07 |
| LTB4R2 | 4.494323 | 4.119455 | −0.12565 | 0.556873 | 0.587541 |
| PBK | 3.231172 | 8.524078 | 1.399486 | 8.66E-12 | 3.08E-11 |
| NOX4 | 0.213872 | 0.914809 | 2.096724 | 7.43E-17 | 6.76E-16 |
| CD63 | 132.3195 | 143.4366 | 0.116388 | 0.0357 | 0.044503 |
| MAVS | 9.091915 | 8.557386 | −0.08741 | 0.058886 | 0.07217 |
| HRC | 15.832 | 2.455079 | −2.689 | 0.000135 | 0.000214 |
| PPP1R13B | 4.357496 | 4.232004 | −0.04216 | 0.406728 | 0.440622 |
| MET | 6.42722 | 16.07803 | 1.322824 | 1.98E-13 | 9.72E-13 |
| RAF1 | 12.84578 | 10.65078 | −0.27033 | 2.34E-08 | 5.47E-08 |
| PARP1 | 14.6988 | 26.57501 | 0.854372 | 1.10E-14 | 6.57E-14 |
| BRCA2 | 0.368605 | 1.089562 | 1.5636 | 1.69E-15 | 1.14E-14 |
| RB1 | 10.35047 | 13.09382 | 0.339189 | 0.001372 | 0.001997 |
| DOCK1 | 6.467952 | 7.398461 | 0.193916 | 0.044576 | 0.055189 |
| HAVCR2 | 1.505471 | 3.462193 | 1.201471 | 8.52E-09 | 2.12E-08 |
| INHBB | 3.192493 | 3.983541 | 0.319368 | 0.187171 | 0.212907 |
| RANBP9 | 25.76165 | 16.33201 | −0.65752 | 8.83E-08 | 1.91E-07 |
| PDCD4 | 46.33207 | 21.70575 | −1.09393 | 4.24E-15 | 2.66E-14 |
| PRPF4B | 7.065991 | 8.054699 | 0.188939 | 0.076818 | 0.093206 |
| SESN1 | 5.243547 | 2.994066 | −0.80844 | 4.58E-08 | 1.02E-07 |
| SESN3 | 6.339101 | 12.12525 | 0.935664 | 0.000134 | 0.000213 |
| PHLDA2 | 27.32433 | 32.44653 | 0.247878 | 0.013174 | 0.017438 |
| ZBTB7A | 15.02226 | 13.14049 | −0.19308 | 0.034407 | 0.043186 |
| CD24 | 322.2363 | 139.3393 | −1.20952 | 3.59E-16 | 3.11E-15 |
| ELANE | 0.362007 | 0.053137 | −2.76823 | 2.24E-11 | 7.55E-11 |
| MDM2 | 4.869839 | 5.64495 | 0.213087 | 0.583262 | 0.608331 |
| KDR | 2.639441 | 2.709828 | 0.037969 | 0.171366 | 0.197397 |
| NFE2L2 | 49.6146 | 42.63778 | −0.21863 | 0.029254 | 0.037326 |
| PRKCI | 8.358897 | 12.9678 | 0.633549 | 8.98E-07 | 1.69E-06 |
| HK2 | 21.87831 | 32.42448 | 0.567582 | 0.003053 | 0.004274 |
| KL | 0.250263 | 0.213245 | −0.23093 | 0.003298 | 0.004583 |
| FGF2 | 0.889105 | 0.818794 | −0.11885 | 0.017626 | 0.023245 |
| EPHB6 | 7.107745 | 4.375857 | −0.69983 | 7.00E-08 | 1.54E-07 |
| CRYAB | 167.0406 | 34.64364 | −2.26954 | 2.03E-09 | 5.45E-09 |
| LTF | 917.6744 | 35.94535 | −4.67411 | 1.04E-12 | 4.45E-12 |
| SDCBP | 23.51988 | 28.08224 | 0.255777 | 0.000704 | 0.001046 |
| MGAT5 | 5.914308 | 8.103987 | 0.454422 | 0.000709 | 0.00105 |
| SPIB | 0.349002 | 2.855308 | 3.032338 | 0.674438 | 0.689594 |
| PDGFRB | 6.27611 | 17.82387 | 1.505868 | 6.29E-12 | 2.33E-11 |
| TLR3 | 2.377006 | 1.523663 | −0.6416 | 2.45E-06 | 4.52E-06 |
| ROCK1 | 3.439256 | 4.891049 | 0.508047 | 1.27E-05 | 2.22E-05 |
| NRAS | 12.33457 | 20.26933 | 0.716591 | 4.09E-11 | 1.29E-10 |
| CASP10 | 2.160351 | 2.674425 | 0.307963 | 0.026357 | 0.033901 |
| PLAT | 14.00419 | 16.83782 | 0.265846 | 0.084598 | 0.102305 |
| PAK4 | 8.152675 | 10.32428 | 0.340695 | 0.001435 | 0.002064 |
| VEGFA | 4.16607 | 10.37621 | 1.316521 | 2.46E-12 | 9.84E-12 |
| PIN1 | 6.35804 | 8.942395 | 0.492079 | 2.32E-07 | 4.85E-07 |
| TWIST1 | 2.615244 | 5.401027 | 1.046288 | 2.01E-08 | 4.75E-08 |
| YWHAZ | 137.0671 | 192.0728 | 0.486771 | 2.00E-05 | 3.45E-05 |
| UBE2C | 10.39057 | 45.27313 | 2.12338 | 3.49E-24 | 2.54E-22 |
| BMP6 | 0.982856 | 1.148606 | 0.224831 | 0.7967 | 0.805553 |
| ELK1 | 8.318122 | 11.98825 | 0.527292 | 7.48E-08 | 1.63E-07 |
| PRDX4 | 26.52284 | 40.26961 | 0.602456 | 1.47E-08 | 3.54E-08 |
| BNIP3 | 7.90732 | 12.83115 | 0.69839 | 0.000114 | 0.000183 |
| BNIP3L | 18.42754 | 22.56428 | 0.292177 | 0.009333 | 0.012444 |
| KDM3A | 3.536094 | 5.264402 | 0.574113 | 9.99E-06 | 1.78E-05 |
| LMO3 | 0.198883 | 0.112174 | −0.82618 | 6.80E-07 | 1.31E-06 |
| TUBB3 | 0.359493 | 1.486287 | 2.047676 | 4.63E-16 | 3.83E-15 |
| SLC2A1 | 60.52895 | 234.2819 | 1.952548 | 3.51E-18 | 4.12E-17 |
| PTPN11 | 14.32772 | 17.24152 | 0.267078 | 0.00128 | 0.001871 |
| PAK3 | 0.212204 | 0.127958 | −0.72979 | 0.004956 | 0.006781 |
| LRP1 | 13.33006 | 19.46389 | 0.546117 | 0.00011 | 0.000177 |
| PIK3R2 | 0.203212 | 0.311395 | 0.615763 | 3.94E-06 | 7.13E-06 |
| PTK6 | 36.58638 | 16.68792 | −1.1325 | 1.26E-07 | 2.68E-07 |
| CDH3 | 32.46422 | 94.52303 | 1.541815 | 1.28E-14 | 7.49E-14 |
| CASP6 | 4.109995 | 6.510983 | 0.663739 | 6.48E-10 | 1.81E-09 |
| CD36 | 4.521261 | 2.358752 | −0.9387 | 0.0185 | 0.024223 |
| EEF2K | 5.583433 | 6.327433 | 0.180468 | 0.254866 | 0.28545 |
| GLO1 | 40.64781 | 65.91452 | 0.697419 | 2.89E-13 | 1.31E-12 |
| LPAR1 | 4.986229 | 4.342499 | −0.19942 | 0.122052 | 0.143777 |
| PAK2 | 13.43084 | 26.75126 | 0.994057 | 7.62E-18 | 8.41E-17 |
| TRAF2 | 5.112718 | 11.24992 | 1.137752 | 1.42E-12 | 5.86E-12 |
| ADCY10 | 0.012564 | 0.098291 | 2.967769 | 5.21E-08 | 1.16E-07 |
| CEACAM1 | 23.81091 | 4.681894 | −2.34646 | 4.30E-16 | 3.64E-15 |
| RBL2 | 7.472103 | 7.919013 | 0.083806 | 0.560895 | 0.590074 |
| SIRPA | 10.44129 | 20.40543 | 0.966653 | 2.01E-09 | 5.42E-09 |
| TNFRSF12A | 17.77236 | 56.28971 | 1.663236 | 3.91E-15 | 2.54E-14 |
| PIK3R3 | 2.852351 | 3.178832 | 0.156345 | 0.320172 | 0.35316 |
| MNX1 | 0.018929 | 0.104106 | 2.45941 | 5.30E-10 | 1.51E-09 |
| APOBEC3G | 1.428213 | 3.617965 | 1.340968 | 2.52E-07 | 5.19E-07 |
| BAG1 | 15.71501 | 11.91024 | −0.39994 | 4.45E-08 | 1.00E-07 |
| IL17A | 0.166524 | 0.067734 | −1.29778 | 0.379319 | 0.41588 |
| COL13A1 | 0.216707 | 1.080756 | 2.318225 | 9.42E-23 | 2.86E-21 |
| RAD9A | 2.494955 | 4.797646 | 0.943313 | 1.30E-12 | 5.50E-12 |
| IFI27 | 39.01783 | 189.8601 | 2.282731 | 2.85E-17 | 2.80E-16 |
| BCL2L15 | 0.762143 | 0.136795 | −2.47804 | 1.60E-15 | 1.12E-14 |
| SNAI2 | 9.426433 | 35.7837 | 1.924519 | 5.63E-23 | 2.28E-21 |
| NOTCH3 | 26.5488 | 40.66437 | 0.615119 | 0.001444 | 0.00207 |
| PTPN1 | 16.33052 | 26.22633 | 0.683445 | 2.80E-13 | 1.29E-12 |
| MYH9 | 127.9836 | 230.4802 | 0.848684 | 4.49E-12 | 1.74E-11 |
| RPS6KB1 | 4.28172 | 4.837179 | 0.175976 | 0.032259 | 0.040631 |
| SIRT1 | 3.624596 | 3.501049 | −0.05003 | 0.231147 | 0.260488 |
| PPP2R1A | 41.01804 | 42.89547 | 0.064567 | 0.582579 | 0.608331 |
| MMP11 | 0.670774 | 26.53 | 5.305655 | 7.32E-25 | 1.33E-22 |
| COL4A2 | 12.47388 | 62.06733 | 2.314924 | 7.08E-21 | 1.61E-19 |
| CD151 | 38.90278 | 67.51187 | 0.795268 | 1.22E-10 | 3.68E-10 |
| ARHGEF7 | 3.293966 | 4.062065 | 0.302388 | 0.000241 | 0.00037 |
| PPP2R5A | 19.17772 | 16.5087 | −0.21621 | 0.000196 | 0.000304 |
| BST2 | 37.59415 | 254.8219 | 2.760909 | 1.32E-18 | 1.65E-17 |
| PPP2R2D | 3.171573 | 4.479758 | 0.498222 | 6.71E-15 | 4.14E-14 |
| CCDC178 | 0.07727 | 0.017247 | −2.16357 | 1.08E-11 | 3.78E-11 |
| SHC1 | 21.34367 | 43.47939 | 1.026524 | 5.25E-17 | 5.03E-16 |
| CDC25C | 0.516771 | 2.219412 | 2.102581 | 7.96E-23 | 2.86E-21 |
| BUB1 | 1.710408 | 5.666885 | 1.728215 | 6.89E-21 | 1.61E-19 |
| FER | 1.387222 | 1.790483 | 0.36815 | 0.004716 | 0.006502 |
| ITGB5 | 16.85811 | 30.79321 | 0.86917 | 7.13E-12 | 2.59E-11 |
| SETD2 | 6.83275 | 6.163023 | −0.14883 | 0.018901 | 0.024659 |
| TP73 | 2.293267 | 4.534157 | 0.98343 | 6.07E-06 | 1.09E-05 |
| BUB3 | 6.926674 | 12.65465 | 0.869433 | 1.71E-20 | 3.12E-19 |
| SLCO1B3 | 0.068606 | 1.145383 | 4.061355 | 6.40E-11 | 1.96E-10 |
| CDK1 | 4.731817 | 14.58463 | 1.623983 | 1.83E-20 | 3.17E-19 |
| MAD2L1 | 1.966104 | 5.783662 | 1.556644 | 2.50E-19 | 3.79E-18 |
| BCL2L2 | 13.45062 | 14.47302 | 0.105693 | 0.380755 | 0.416201 |
| TDGF1 | 0.049071 | 0.038191 | −0.36164 | 0.002382 | 0.00336 |
| PDCD6IP | 20.40737 | 15.41152 | −0.40508 | 5.27E-07 | 1.05E-06 |
| SH3GLB1 | 20.13678 | 16.61214 | −0.27759 | 5.38E-07 | 1.06E-06 |
| EDAR | 1.496716 | 0.717442 | −1.06087 | 0.0001 | 0.000162 |
| DYNLL2 | 15.39156 | 15.21008 | −0.01711 | 0.417521 | 0.449638 |
| TSC2 | 6.322719 | 7.11398 | 0.170112 | 0.642709 | 0.662736 |
| MAP3K7 | 4.586373 | 6.371236 | 0.47422 | 6.69E-12 | 2.46E-11 |
| BAG4 | 3.665205 | 6.3014 | 0.781778 | 1.34E-06 | 2.51E-06 |
| F10 | 1.573231 | 0.37288 | −2.07695 | 8.72E-12 | 3.08E-11 |
| F3 | 66.70473 | 69.75341 | 0.064475 | 0.876845 | 0.881689 |
| HSP90B1 | 94.82423 | 192.3032 | 1.020055 | 5.37E-20 | 8.89E-19 |
| ADAMTSL1 | 0.271072 | 0.241255 | −0.16812 | 0.406728 | 0.440622 |
| SERPINB1 | 244.5921 | 96.74976 | −1.33805 | 2.71E-08 | 6.23E-08 |
| MAP3K1 | 5.753347 | 4.497959 | −0.35513 | 0.00142 | 0.002059 |
| CTBP1 | 10.54307 | 12.70683 | 0.269309 | 0.000138 | 0.000217 |
| CEACAM4 | 0.316645 | 0.506744 | 0.678393 | 0.000521 | 0.000781 |
| PXN | 10.019 | 24.16003 | 1.269883 | 8.91E-16 | 6.49E-15 |
| MALAT1 | 7.392316 | 11.12716 | 0.589986 | 0.002796 | 0.00393 |
| IKBKG | 1.415399 | 2.336568 | 0.723183 | 2.15E-14 | 1.24E-13 |
| TFDP1 | 23.83973 | 36.49752 | 0.614431 | 1.10E-07 | 2.36E-07 |
| CRYBA1 | 0.019411 | 0.0461 | 1.247931 | 6.72E-05 | 0.00011 |
| SERPINE1 | 15.19701 | 128.4948 | 3.07985 | 8.58E-19 | 1.20E-17 |
| ACTG1 | 1413.665 | 1441.546 | 0.028177 | 0.486353 | 0.517638 |
| ARHGDIA | 73.53997 | 100.7372 | 0.453996 | 3.50E-09 | 9.29E-09 |
| EZR | 188.4719 | 167.367 | −0.17133 | 0.18452 | 0.210549 |
| SLC39A6 | 18.26425 | 34.19764 | 0.904874 | 4.64E-11 | 1.46E-10 |
| TIAM1 | 8.254501 | 5.602011 | −0.55924 | 0.001435 | 0.002064 |
| PDPK1 | 2.547682 | 2.518078 | −0.01686 | 0.586687 | 0.610155 |
| SMAD7 | 3.674136 | 6.377043 | 0.795483 | 7.13E-09 | 1.80E-08 |
| NTRK3 | 0.203377 | 0.040956 | −2.312 | 2.78E-11 | 8.96E-11 |
| RHOC | 23.32079 | 46.03098 | 0.980989 | 9.99E-14 | 5.35E-13 |
| CASP2 | 3.633341 | 5.997788 | 0.723134 | 5.83E-09 | 1.52E-08 |
| TNC | 23.51883 | 115.6361 | 2.297704 | 3.63E-12 | 1.42E-11 |
| IRF6 | 48.96966 | 80.54532 | 0.717913 | 3.95E-09 | 1.04E-08 |
| HOTAIR | 0.015786 | 0.299069 | 4.243791 | 1.96E-18 | 2.38E-17 |
| GNE | 9.979346 | 4.104163 | −1.28186 | 3.75E-06 | 6.83E-06 |
| XAF1 | 0.786112 | 3.071366 | 1.966074 | 2.10E-12 | 8.50E-12 |
| SFRP1 | 31.93154 | 9.283172 | −1.78229 | 5.34E-11 | 1.65E-10 |
| MAP2K2 | 23.03109 | 25.34606 | 0.138179 | 0.21158 | 0.239923 |
| CSK | 21.29519 | 20.78194 | −0.0352 | 0.603951 | 0.626319 |
| PIK3C2B | 4.860598 | 3.072133 | −0.66189 | 2.20E-07 | 4.62E-07 |
| FOXC2 | 0.480331 | 2.196439 | 2.193067 | 1.07E-08 | 2.64E-08 |
| TAGLN | 28.95494 | 31.34963 | 0.114639 | 0.028235 | 0.036189 |
| ENDOG | 5.263162 | 5.11662 | −0.04074 | 0.545555 | 0.577273 |
| ARHGDIB | 39.03633 | 43.80943 | 0.166424 | 0.436075 | 0.468233 |
| FBLIM1 | 12.32337 | 29.4257 | 1.25568 | 1.65E-13 | 8.35E-13 |
| CCDC80 | 11.16683 | 6.947347 | −0.68469 | 0.319203 | 0.35316 |
| RACK1 | 180.8739 | 165.0623 | −0.13197 | 0.004925 | 0.006765 |
| PRKD1 | 0.489846 | 0.67399 | 0.460399 | 0.27101 | 0.3026 |
| LDHA | 112.4477 | 197.3562 | 0.811548 | 2.67E-11 | 8.75E-11 |
| ANXA2 | 162.2405 | 185.6451 | 0.194413 | 0.131976 | 0.154468 |
| SPP1 | 15.36975 | 106.3315 | 2.790404 | 2.30E-14 | 1.31E-13 |
| SMARCE1 | 4.339046 | 4.790058 | 0.142665 | 0.141973 | 0.165635 |
| QSOX1 | 24.84684 | 24.39677 | −0.02637 | 0.755469 | 0.768131 |
| RBFOX2 | 6.980204 | 9.965431 | 0.513663 | 5.26E-10 | 1.51E-09 |
| CDC42 | 59.05889 | 70.64329 | 0.258398 | 2.87E-05 | 4.94E-05 |
| MAOA | 16.12035 | 12.17683 | −0.40474 | 0.000768 | 0.001132 |
| PIP5K1C | 6.782737 | 8.769851 | 0.370685 | 1.04E-05 | 1.83E-05 |
| JUP | 372.3741 | 443.692 | 0.252806 | 0.101442 | 0.122267 |
| ATF2 | 4.480363 | 6.447307 | 0.525081 | 7.87E-07 | 1.49E-06 |
| OCLN | 2.359423 | 0.894399 | −1.39944 | 1.37E-12 | 5.72E-12 |
| CRABP2 | 250.8156 | 185.2496 | −0.43716 | 0.061468 | 0.074831 |
| ID2 | 15.48896 | 12.54592 | −0.30402 | 0.043013 | 0.053436 |
| PITPNC1 | 3.027077 | 3.06002 | 0.015616 | 0.70824 | 0.722127 |
| AFAP1L1 | 2.98005 | 4.975255 | 0.739434 | 5.90E-07 | 1.15E-06 |
| NGF | 0.891798 | 2.084751 | 1.225086 | 1.08E-05 | 1.89E-05 |
| PCNA | 43.90651 | 103.8344 | 1.241778 | 2.06E-17 | 2.10E-16 |
| GSK3B | 7.186319 | 11.53488 | 0.682678 | 1.91E-11 | 6.57E-11 |
| TP63 | 31.46696 | 73.17857 | 1.217583 | 2.05E-13 | 9.96E-13 |
| KRT14 | 2927.466 | 5905.31 | 1.01236 | 1.65E-05 | 2.86E-05 |
| SPHK1 | 7.077903 | 17.8197 | 1.332079 | 5.07E-16 | 4.01E-15 |
| CTNNA1 | 57.16702 | 44.32257 | −0.36714 | 0.00382 | 0.005288 |
| NDRG1 | 91.60225 | 241.6854 | 1.399675 | 3.02E-11 | 9.63E-11 |
| OGT | 5.529156 | 8.215424 | 0.571276 | 1.67E-06 | 3.10E-06 |
| EHMT2 | 5.868161 | 9.019899 | 0.620203 | 6.26E-09 | 1.62E-08 |
| RAC3 | 3.490052 | 11.18945 | 1.680818 | 1.91E-08 | 4.54E-08 |
| SIRT6 | 4.728459 | 7.677568 | 0.699279 | 1.58E-13 | 8.10E-13 |
| ACP1 | 11.21575 | 16.36896 | 0.545438 | 1.66E-12 | 6.79E-12 |
| FOXA1 | 7.238367 | 3.935025 | −0.87929 | 2.16E-08 | 5.08E-08 |
| ONECUT1 | 0.001954 | 0.036779 | 4.234257 | 4.36E-13 | 1.91E-12 |
| SRSF3 | 29.34989 | 35.06791 | 0.256796 | 0.001737 | 0.002461 |