Table 5.

H-bond and hydrophobic interaction between high binding score compounds and receptors

Drugs	H-Bond Interactions	Hydrophobic Interactions
Bictegravir	HIS41, LEU141, CYS145, HIS164	-
Emtricitabine	MET49, TYR54	HIS41, CYS44, PRO52, GLY143, CYS145, HIS164, MET165, GLU166, ASP187, ARG188, GLN189
Entecavir	THR26, LEU141, HIS163, GLY144, GLU166	THR25, LEU27, HIS41, MET49, PHE140, ASN142, MET165, HIS170
Lamuvidune	ASP187	HIS41, PRO52, TYR54, GLY143, CYS145, HIS164, MET165, GLU166, ARG188, GLN189
Tenofovir	HIS41, CYS145, LEU141, ASN142, GLY143, GLU166	THR26, LEU27, TYR54, PHE140, SER144, HIS163, MET165, HIS172, ASP187, ARG188, GLN189, THR190, GLN192
Oseltamivir	CYS145, GLU166, GLN189	THR25, LEU27, TYR54, PHE140, GLY143, HIS163, HIS164, HIS172, ASP187, ARG188
Ribavirin	HIS41, LEU141, CYS145, HIS164	MET49, PHE140, ASN142, GLY143, GLU166, MET165, HIS172, ASP187, ARG188, GLN189
Favipiravir	LEU141, GLY143, SER144, CYS145, GLU166	PHE140, ASN142, HIS163, MET165
Hydroxychloroquine	GLU166, GLN189, THR190	HIS41, PHE140, LEU141, ASN142, GLY143, SER144, HIS164, MET165, HIS172
Lopinavir	MET165, GLU166, GLN189	TYR24, THR25, THR26, MET49, PHE140, LEU141, ASN142, GLY143, SER144, LEU167, ARG188, THR190, GLN192
Remdevisir	THR26, PHE140, LEU141, GLU166	THR25, LEU27, ASN142, GLY143, SER144, CYS145, HIS163, HIS164, HIS172, ARG188, GLN189
Ritonavir	LYS5, ASN133, ASP197, GLU288	-