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. 2023 Mar 25;36:100749. doi: 10.1016/j.lanwpc.2023.100749

Table 3.

Detailed characteristics of patients not achieving SVR12.

Characteristics Study patients
06K003 06K005 06K019 06K035 18C2027 18K024
SVR 12 No No No No No No
Age, years 38 47 42 50 51 55
Gender Female Female Male Male Male Male
HCV/HIV transmission PWID Unknown PWID PWID PWID Unknown
Adherence 100% 100% 100% 100% 100% 100%
Adverse event No Constipation Urinary tract infection No No No
At baseline
 HCV genotype 3b 6n 3b 2a 3b 3b
 Previous anti-HCV treatment No Interferon plus ribavirin No No No No
 HCV RNA, log10 IU/mL 3.5 6.7 3.7 6.6 7.0 6.9
 HIV RNA <20 copies/ml <20 copies/ml <20 copies/ml <20 copies/ml <20 copies/ml <20 copies/ml
 FIB-4 score 0.71 1.33 4.32 3.47 4.28 3.56
 CD4 count 640 1486 127 713 244 295
At relapse
 HCV RNA, log10 IU/mL 6.7 5.7 1.9 6.3 5.3 6.8
 FIB-4 score 1.07 1.97 6.58 2.11 3.87 2.43
 CD4 count 971 762 145 Unavailable 448 236
 HIV RNA <20 copies/ml <20 copies/ml <20 copies/ml <20 copies/ml <20 copies/ml <20 copies/ml

Abbreviations: HCV, hepatitis C virus; HIV, human immunodeficiency virus; PWID, people who inject drugs; FIB-4 Fibrosis 4 marker.