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. 2023 Jul 6;24(8):e56525. doi: 10.15252/embr.202256525

Figure EV4. Comparison of En1‐Het and scFvEN1‐expressing mice phenotypes.

Figure EV4

Comparison between En1‐het mouse and scFvEN1 models. Data and graphs are from main figures (primarily Figs 2 and 4). WT mice injected with scFvEN1 show similar results to those obtained in the En1‐Het mouse with a milder strength loss, a smaller decrease in the number of fully occupied endplates, and the specific loss of large‐size αMNs. At 7 months, scFvEN1 injected mice have a phenotype similar to 3‐month‐old En1‐Het mice.