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Functional studies of the PROTACs on cell viability, cell cycle progression and cell apoptosis. (A) AlamarBlue™ Cell Viability. MV4;11 cells were treated by 13, 9, (+)-JQ1 and 13NT for 72 h. (B) MV4;11 cells were treated by indicated dosage of 13 for 48 h followed by flow cytofluorimetric cell cycle analysis. (C) and (D) MV4;11 cells were treated by indicated dosage of 13 for 48 h followed by flow cytofluorimetric apoptosis analyses.
