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. Author manuscript; available in PMC: 2024 Feb 23.
Published in final edited form as: J Med Chem. 2023 Feb 7;66(4):2904–2917. doi: 10.1021/acs.jmedchem.2c01941

Scheme 1.

Scheme 1.

Relative binding affinities of substituted PDHUs in a fluorescent polarization assay. Lenalidomide 1C was used as the positive control and each compound was tested three times.