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. 2023 Jul 7;62(15):2238–2243. doi: 10.1021/acs.biochem.3c00189

Figure 1.

Figure 1

Chemical structures of AdK substrates and inhibitors. (A) AdK interconversion of its substrates ATP and AMP into two ADP with Mg2+ as cofactor. (B) The inhibitor AP5A that leads to a closed enzyme conformation. (C) AP4A (studied here).