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. 1999 Feb;73(2):1645–1648. doi: 10.1128/jvi.73.2.1645-1648.1999

FIG. 3.

FIG. 3

HIV-1 coreceptor function of G/S insertions in the Nt of CCR5. Seven, 14, or 21 alternating glycine/serine residues were inserted between P19 and C20 of the Nt domain of CCR5. Coreceptor activity of these insertion mutants was tested in U87MG-CD4 cells by using NLluc+env−/JR-FL (shaded bars) and NLluc+env−/Gun-1 (open bars). The coreceptor activity of each mutant is expressed as a percentage of wild-type (wt) CCR5 activity and is standardized for protein expression levels (see legend to Fig. 1).