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. 2023 Jul 20;14:1165106. doi: 10.3389/fimmu.2023.1165106

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Copyright © 2023 Wang, Shan, Li and Zuo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical presentation before and after therapy in case 1. Erythematous patches and tense bullae appear on the trunk, extremities, and hands before treatment (A–C). Bullae and crusting disappeared with hyperpigmentation (D–F) after 14 weeks of treatment with dupilumab combined with immunosuppressive therapy.