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Risk ratios (RR), and 95% confidence intervals (CI), estimating the association between low adherence to treatment (PDC < 25%) and single-pill combination vs. the two-pill combination. Three categories were considered for the clinical profile according to the Multisource Comorbidity Score (MCS): good (0 ≤ MCS ≤ 4), intermediate (5 ≤ MCS ≤ 14), and poor (MCS ≥ 15).
