Table 5.
Clinical outcomes in PACC
| Reference | Data source | Years | n | Age at diagnosis (median) | Median tumor size (cm) | With metastasis (%) | OS (median) | Stage 4 OS (median) | Early stage OS (median) |
|---|---|---|---|---|---|---|---|---|---|
| [142] | NCDB | 1985-2005 | 865 | 67 | ]5.9 | 32.1 | N/A | 17.2%* | NR-22.6m |
| [145] | SEER | 1988-2003 | 672 | 56 | 53.1 | 47 | 22%* | 72%*^ | |
| [144] | SEER | 2004-2016 | 252 | 63.8 | N/A | 54.4 | 10 | 7 | 18,29^ |
| [143] | German Cancer Registry Group | 2000-2019 | 233 | 66 | N/A | 33.9 | 22 | 6 | 34^ |
| [141] | SI-Harvard Hospitals | 1996-2019 | 66 | 64 | 4.3 | 42 | 13 | 15 | 38 |
| [147] | Korean Tumor Registry System | 2003-2018 | 59 | 59.2 | 4.6 | 0 | N/A | N/A | 78.8^ |
| [148] | SI-West China Hospital | 2006-2016 | 52 | 50.8 | 5.0 | 30.8 | 39 | N/A | 48^ |
| Seo 2017 | SI-Asan Medical Center | 1997-2015 | 20 | 57 | 4.0 | 0 | N/A | N/A | 75^ |
| Matos 2009 | MI | 1998-2008 | 17 | 59 | 5.3 | 23.5 | 19 | N/A | 61^ |
Multiple retrospective case series examining survival in PACC patients have been conducted.
*
indicates that 5-year overall survival percentage is documented;
^
indicates value is for resected patients only;
SI: Single institution; MI: multi-institution; n: number of patient cases; OS: overall survival; N/A: not available; NR: not reached.