Table 2.
Genes that were downregulated in the kidneys of CKO mice compared with Cont mice
| Gene Symbol | Gene Name | Fold Change | Genbank Accession |
|---|---|---|---|
| Hmgcs2 | 3-Hydroxy-3-methylglutaryl-coenzyme A synthase 2 | 0.187 | NM_008256 |
| Zdhhc19 | Zinc finger, DHHC domain containing 19 | 0.206 | NM_199309 |
| Hmgcs2 | 3-Hydroxy-3-methylglutaryl-coenzyme A synthase 2 | 0.206 | NM_008256 |
| Kynu | Kynureninase | 0.222 | NM_001289593 |
| Slc7a12 | Solute carrier family 7 (cationic amino acid transporter, y+system), member 12 | 0.227 | NM_080852 |
| Kynu | Kynureninase | 0.249 | NM_027552 |
| Crabp1 | Cellular retinoic acid binding protein I | 0.267 | NM_001284507 |
| Prlr | Prolactin receptor | 0.309 | NM_001253781 |
| Creb3l3 | cAMP responsive element binding protein 3-like 3 | 0.315 | NM_145365 |
| Prlr | Prolactin receptor | 0.335 | NM_011169 |
| Prlr | Prolactin receptor | 0.342 | NM_011169 |
| Antxr1 | Anthrax toxin receptor 1 | 0.346 | NM_054041 |
| Fabp1 | Fatty acid binding protein 1, liver | 0.383 | NM_017399 |
| Mbl2 | Mannose-binding lectin (protein C) 2 | 0.390 | NM_010776 |
| Antxr1 | Anthrax toxin receptor 1 | 0.393 | AK031465 |
| Depp1 | DEPP1 autophagy regulator | 0.397 | NM_145980 |
| Rab6b | RAB6B, member RAS oncogene family | 0.405 | NM_173781 |
| S100a14 | S100 calcium binding protein A14 | 0.425 | NM_025393 |
| Ang3 | Angiogenin, ribonuclease A family, member 3 | 0.426 | NM_001123394 |
| Ang | Angiogenin, ribonuclease, RNase A family, 5 | 0.427 | NM_007447 |
| B930025P03Rik | RIKEN cDNA B930025P03 gene | 0.428 | NR_040705 |
| Lrriq1 | Leucine-rich repeats and IQ motif containing 1 | 0.429 | NM_001163559 |
| Igfbp1 | Insulin-like growth factor binding protein 1 | 0.431 | NM_008341 |
| Klra22 | Killer cell lectin-like receptor subfamily A, member 22 | 0.436 | NM_053152 |
| Otos | Otospiralin | 0.438 | NM_153114 |
| Cry2 | Cryptochrome 2 (photolyase-like) | 0.442 | AK037778 |
| Ang4 | Angiogenin, ribonuclease A family, member 4 | 0.447 | NM_177544 |
| Gzma | Granzyme A | 0.450 | NM_010370 |
| Cyp24a1 | Cytochrome P450, family 24, subfamily a, polypeptide 1 | 0.451 | NM_009996 |
| Slc13a1 | Solute carrier family 13 (sodium/sulfate symporters), member 1 | 0.454 | AK047580 |
| 2900060L22Rik | RIKEN cDNA 2900060L22 gene | 0.458 | XR_869289 |
| 5730405A17Rik | RIKEN cDNA 5730405A17 gene | 0.458 | AK017489 |
| Baiap3 | BAI1-associated protein 3 | 0.459 | NM_001163270 |
| Ang6 | Angiogenin, ribonuclease A family, member 6 | 0.460 | NM_001011876 |
| Gm40787 | Predicted gene, 40787 | 0.460 | XR_872127 |
| Lgr5 | Leucine-rich repeat containing G protein coupled receptor 5 | 0.461 | NM_010195 |
| Sema5b | Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM), and short cytoplasmic domain, (semaphorin) 5B | 0.462 | NM_013661 |
| Gm16010 | Predicted gene 16010 | 0.462 | AK085341 |
| Rnase4 | Ribonuclease, RNase A family 4 | 0.464 | NM_021472 |
| Slc13a1 | Solute carrier family 13 (sodium/sulfate symporters), member 1 | 0.466 | AK019876 |
| Gm525 | Predicted gene 525 | 0.475 | NM_001033266 |
| Gm36283 | Predicted gene, 36283 | 0.480 | XR_380771 |
| Pde6h | Phosphodiesterase 6H, cGMP-specific, cone, γ | 0.482 | BC057290 |
| 0.483 | AK051762 | ||
| Gm4340 | Predicted gene 4340 | 0.486 | NM_001177535 |
| LOC101056011 | Uncharacterized LOC101056011 | 0.492 | AK140221 |
| 8430419K02Rik | RIKEN cDNA 8430419K02 gene | 0.494 | XR_872264 |
| Scgb1c1 | Secretoglobin, family 1C, member 1 | 0.495 | NM_001099742 |
| Aqp6 | Aquaporin 6 | 0.498 | DQ826418 |
| Nmrk1 | Nicotinamide riboside kinase 1 | 0.498 | LF257405 |
| Slc26a7 | Solute carrier family 26, member 7 | 0.498 | NM_145947 |
| Procr | Protein C receptor, endothelial | 0.505 | NM_011171 |
| 4732416N19Rik | RIKEN cDNA 4732416N19 gene | 0.508 | NR_015615 |
| Sema5b | Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM), and short cytoplasmic domain, (semaphorin) 5B | 0.510 | AK078659 |
| Cry2 | Cryptochrome 2 (photolyase-like) | 0.511 | AK041696 |
| 2900052L18Rik | RIKEN cDNA 2900052L18 gene | 0.512 | NR_151480 |
| Slc51a | Solute carrier family 51, α subunit | 0.512 | NM_145932 |
| Aplnr | Apelin receptor | 0.513 | NM_011784 |
| Itga8 | Integrin α 8 | 0.513 | AK044910 |
| Slc40a1 | Solute carrier family 40 (iron-regulated transporter), member 1 | 0.514 | AK165333 |
| Gm10824 | Predicted gene 10824 | 0.514 | AK033378 |
| Gm40798 | Predicted gene, 40798 | 0.516 | AK042269 |
| Tnfsf15 | Tumor necrosis factor (ligand) superfamily, member 15 | 0.517 | NM_177371 |
| Olfr1500 | Olfactory receptor 1500 | 0.518 | NM_001011831 |
| Slc51a | Solute carrier family 51, α subunit | 0.518 | AK147155 |
| Ccdc116 | Coiled-coil domain containing 116 | 0.519 | XM_006522712 |
| Gm32133 | Predicted gene, 32133 | 0.519 | XR_379717 |
| Aqp6 | Aquaporin 6 | 0.520 | NM_175087 |
| Tekt1 | Tektin 1 | 0.520 | NM_001282006 |
| Pdia2 | Protein disulfide isomerase associated 2 | 0.521 | NM_001081070 |
| Gm15230 | Predicted gene 15230 | 0.522 | XR_387114 |
| Igf1r | Insulin-like growth factor I receptor | 0.523 | AK155079 |
| Gm26588 | Predicted gene, 26588 | 0.523 | XR_377840 |
| Ptch1 | Patched 1 | 0.523 | XM_011244497 |
| 4930539N22Rik | RIKEN cDNA 4930539N22 gene | 0.524 | NR_040598 |
| AI662168 | Expressed sequence AI662168 | 0.525 | AI662168 |
| Eif4e1b | Eukaryotic translation initiation factor 4E family member 1B | 0.527 | NM_001033269 |
| Acot3 | Acyl-CoA thioesterase 3 | 0.529 | NM_001346701 |
| Acot3 | Acyl-CoA thioesterase 3 | 0.529 | NM_134246 |
| Ypel1 | Yippee like 1 | 0.530 | AK163365 |
| Pik3ip1 | Phosphoinositide-3-kinase interacting protein 1 | 0.530 | NM_178149 |
| Actn3 | Actinin α 3 | 0.532 | NM_013456 |
| Enpp1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.533 | AK035402 |
| Cryaa | Crystallin, α A | 0.533 | NM_001278569 |
| Prnd | Prion like protein doppel | 0.534 | NM_023043 |
| Tcstv3 | 2 Cell-stage, variable group, member 3 | 0.534 | NM_153523 |
| Nek5 | NIMA (never in mitosis gene a)-related expressed kinase 5 | 0.534 | AK054168 |
| Iigp1 | Interferon inducible GTPase 1 | 0.536 | AK172047 |
| Clec7a | C-type lectin domain family 7, member a | 0.537 | NM_020008 |
| Timm8a2 | Translocase of inner mitochondrial membrane 8A2 | 0.538 | NM_001037744 |
| Bfsp1 | Beaded filament structural protein 1, in lens-CP94 | 0.539 | NM_001291061 |
| Gm17762 | Predicted gene, 17762 | 0.539 | AK033161 |
| Tnnt2 | Troponin T2, cardiac | 0.541 | AK086260 |
| Nr5a2 | Nuclear receptor subfamily 5, group A, member 2 | 0.541 | NM_030676 |
| Olfr10 | Olfactory receptor 10 | 0.542 | NM_206822 |