Table 3.
Adverse effects.
| Total (N = 71) | % |
Mono
(N = 47) |
% |
Combo
(N = 24) |
% |
Bica
(N = 4) |
% |
Abi
(N = 8) |
% |
Enza
(N = 10) |
% |
Apa
(N = 3) |
% |
Doce
(N = 1) |
% |
Cab
(N = 2) |
% |
Radium
(N = 1) |
% | |
| Hot flash | 28 | 39 | 19 | 40 | 9 | 38 | 1 | 25 | 3 | 38 | 4 | 40 | 1 | 33 | 0 | 0 | 0 | 0 | 1 | 100 |
| Fatigue | 18 | 25 | 9 | 19 | 9 | 38 | 1 | 25 | 4 | 50 | 3 | 30 | 1 | 33 | 1 | 100 | 1 | 50 | 1 | 100 |
| Diarrhea | 4 | 6 | 3 | 6 | 1 | 4 | 0 | 0 | 0 | 0 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Const | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Pain | 10 | 14 | 3 | 6 | 7 | 29 | 1 | 25 | 3 | 38 | 3 | 30 | 1 | 33 | 1 | 100 | 1 | 50 | 0 | 0 |
| Weight gain | 11 | 15 | 6 | 13 | 5 | 21 | 1 | 25 | 3 | 38 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 100 |
| Urinary | 13 | 18 | 12 | 26 | 1 | 4 | 0 | 0 | 0 | 0 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Adverse effects MACE | ||||||||||||||||||||
| Total (N = 71) | % | Mono (N = 47) |
% | Combo (N = 24) |
% | Bica (N = 4) |
% | Abi (N = 8) |
% | Enza (N = 10) |
% | Apa (N = 3) |
% | Doce (N = 1) |
% | Cab (N = 2) |
% | Radium (N = 1) |
% | |
| Total w/MACE | 5 | 7 | 4 | 9 | 1 | 4 | 0 | 0 | 0 | 0 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| MI | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| CVA/TIA | 2 | 3 | 1 | 2 | 1 | 4 | 0 | 0 | 0 | 0 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Revascularization | 2 | 3 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| HF event | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abbreviations: Abi, abiraterone; Apa, apalutamide; Bica, bicalutamide; Cab, cabazitaxel; Combo, combination therapy; CVA/TIA, cerebral vascular accident/transient ischemic attack; Doce, docetaxel; HF event, heart failure hospitalization; MACE, major adverse cardiac events; MI, myocardial infarction; Mono, monotherapy; Radium, Radium 223.