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PTEN mutation as predictor of post-CDKi disease progression. (A) Frequency of mutations among subset of 37 patients with available clinical NGS prior to CDKi initiation. All but 4 of these patients had >1 mutation (of the 12 genes we analyzed). (B) Post-CDKi PFS Kaplan-Meier curves by pre-CDKi PTEN mutational status.
