Table 2.
Total number and percentages of in vitro antimicrobial susceptibility test for common selected Gram-negative organisms collected from blood, intra-abdominal, respiratory and UTIs in the SMART Study (2017–2019)
| Species | No. of isolates | AST | Amikacin | Aztreonam | Cefepime | Cefotaxime | Cefoxitin | Ceftazidime | Ceftazidime-avibactam | Ceftolozane-tazobactam | Ceftriaxone | Ciprofloxacin | Colistin | Ertapenem | Imipenem | Imipenem-relebactam | Levofloxacin | Meropenem | Meropenem-vaborbactam | Piperacillin-tazobactam | Tobramycin |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Escherichia coli | 209 | No. of tested isolates | 209 | 209 | 209 | 72 | 209 | 209 | 137 | 209 | 209 | 145 | NA | 209 | 209 | 209 | 209 | 209 | 64 | 209 | NA |
| Susceptible (%) | 205 (98.09%) | 104 (49.76%) | 107 (51.20%) | 28 (38.89%) | 143 (68.42%) | 107 (51.20%) | 132 (96.35%) | 188 (89.95%) | 92 (44.02%) | 52 (35.86%) | 198 (94.74%) | 201 (96.17%) | 203 (97.13%) | 55 (26.32%) | 201 (96.17%) | 62 (96.88%) | 179 (85.65%) | ||||
| Klebsiella pneumoniae | 187 | No. of tested isolates | 187 | 187 | 187 | 70 | 187 | 187 | 117 | 187 | 187 | 129 | NA | 187 | 187 | 187 | 187 | 187 | 58 | 187 | NA |
| Susceptible (%) | 179 (95.72%) | 124 (66.31%) | 122 (65.24%) | 45 (64.29%) | 144 (77.01%) | 120 (64.17%) | 110 (94.02%) | 159 (85.03%) | 114 (60.96%) | 77 (59.69%) | 160 (85.56%) | 161 (86.10%) | 165 (88.24%) | 77 (41.18%) | 163 (87.17%) | 50 (86.21%) | 140 (74.87%) | ||||
| Pseudomonas aeruginosa | 164 | No. of tested isolates | 164 | 164 | 164 | NA | NA | 164 | 111 | 164 | NA | 99 | 164 | NA | 164 | 164 | 164 | 164 | NA | 164 | 111 |
| Susceptible (%) | 160 (97.56%) | 105 (64.02%) | 126 (76.83%) | 120 (73.17%) | 104 (93.69%) | 156 (95.12%) | 51 (51.52%) | 0 (0.00%) | 115 (70.12%) | 150 (91.46%) | 125 (76.22%) | 120 (73.17%) | 112 (68.29%) | 108 (97.30%) | |||||||
| Stenotrophomonas maltophilia | 45 | No. of tested isolates | NA | NA | NA | NA | NA | 45 | NA | NA | NA | NA | NA | NA | NA | NA | 45 | NA | NA | NA | NA |
| Susceptible (%) | 15 (33.33%) | 34 (75.56%) | |||||||||||||||||||
| Enterobacter cloacae | 26 | No. of tested isolates | 26 | 26 | 26 | 13 | 26 | 26 | 16 | 26 | 26 | 22 | NA | 26 | 26 | 26 | 26 | 26 | 7 | 26 | NA |
| Susceptible (%) | 25 (96.15%) | 20 (76.92%) | 23 (88.46%) | 8 (80%) | 1 (4.35%) | 20 (76.92%) | 16 (100%) | 20 (76.92%) | 19 (27.08%) | 16 (84.21%) | 23 (88.46%) | 23 (88.46%) | 24 (92.31%) | 16 (61.54%) | 24 (92.31%) | 7 (100%) | 20 (76.92%) | ||||
| Serratia marcescens | 20 | No. of tested isolates | 20 | 20 | 20 | 7 | 20 | 20 | 13 | 20 | 20 | 10 | 20 | 20 | 20 | 20 | 20 | 10 | 20 | NA | |
| Susceptible (%) | 20 (100%) | 20 (100%) | 19 (95%) | 7 (100%) | 1 (5%) | 20 (100%) | 13 (100%) | 19 (95%) | 17 (85%) | 9 (90%) | NA | 19 (95%) | 14 (70%) | 17 (85%) | 11 (55%) | 19 (95%) | 9 (90%) | 18 (90%) | |||
| Acinetobacter baumannii | 19 | No. of tested isolates | 19 | NA | 19 | 9 | NA | 19 | NA | NA | 9 | 19 | 19 | NA | 19 | NA | 19 | 19 | NA | 19 | 11 |
| Susceptible (%) | 12 (63.16%) | 11 (57.89%) | 2 (25.00%) | 12 (63.16%) | 0 | 8 (61.54%) | 0 | 12 (63.16%) | 11 (57.89%) | 12 (63.16%) | 11 (57.89%) | 8 (72.73%) | |||||||||
| Klebsiella aerogenes | 11 | No. of tested isolates | 11 | 11 | 11 | 5 | 11 | 11 | 6 | 11 | 11 | 9 | 11 | 11 | 11 | 11 | 11 | 11 | 2 | 11 | NA |
| Susceptible (%) | 11 (100%) | 9 (81.82%) | 11 (100%) | 3 (60.00%) | 0 | 8 (72.73%) | 6 (100%) | 10 (90.91%) | 8 (72.73%) | 6 (66.67%) | 11 (100%) | 11 (100%) | 10 (90.91%) | 11 (100%) | 5 (45.45%) | 11 (100%) | 2 (100%) | 9 (81.82%) | |||
| Proteus mirabilis | 10 | No. of tested isolates | 10 | 10 | 10 | 4 | 10 | 10 | 6 | 10 | 10 | 7 | NA | 10 | 10 | 10 | 10 | 10 | 3 | 10 | NA |
| Susceptible (%) | 10 (100%) | 9 (90%) | 9 (90%) | 2 (50.00%) | 9 (90%) | 9 (90%) | 6 (100%) | 9 (90%) | 8 (80%) | 5 (71.43%) | 10 (100%) | 8 (80%) | 9 (90%) | 5 (50%) | 10 (100%) | 3 (100%) | 10 (100%) | ||||
| Klebsiella variicola | 8 | No. of tested isolates | 8 | 8 | 8 | 1 | 8 | 8 | 7 | 8 | 8 | 4 | NA | 8 | 8 | 8 | 8 | 8 | 4 | 8 | NA |
| Susceptible (%) | 8 (100%) | 8 (100%) | 8 (100%) | 1 (100%) | 8 (100%) | 8 (100%) | 7 (100%) | 8 (100%) | 8 (100%) | 4 (100%) | 6 (75%) | 6 (75%) | 6 (75%) | 7 (87.5%) | 7 (87.5%) | 4 (100%) | 6 (75%) |
Susceptibility tests were reported according to breakpoints of the CLSI 2020 Edition.