Table 3. Spatial overlap accuracy in the automated quantification of total abnormalities and fibrosis score on the original and converted CT images in each group.
| CT patterns | Group | Spatial overlap accuracy metric | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| DSC | Pixel-wise recall | Pixel-wise precision† | ||||||||
| Original CT (1) | Converted CT (2) | Difference [(2)-(1)] | Original CT (1) | Converted CT | Difference [(2)-(1)] | Original CT (1) | Converted CT (2) | Difference‡[(2)-(1)] | ||
| Total abnormalities | Group 2 | 0.62 ± 0.23 | 0.68 ± 0.18 | 0.06* | 0.61 ± 0.25 | 0.64 ± 0.22 | 0.04 | 0.71 ± 0.16 | 0.79 ± 0.14 | 0.05* |
| Group 3 | 0.63 ± 0.21 | 0.70 ± 0.19 | 0.05* | 0.64 ± 0.25 | 0.69 ± 0.24 | 0.05* | 0.75 ± 0.18 | 0.79 ± 0.15 | 0.04* | |
| Group 4 | 0.56 ± 0.21 | 0.65 ± 0.20 | 0.06* | 0.66 ± 0.22 | 0.72 ± 0.20 | 0.06* | 0.63 ± 0.26 | 0.67 ± 0.25 | 0.04* | |
| Group 5 | 0.64 ± 0.17 | 0.68 ± 0.16 | 0.04* | 0.71 ± 0.19 | 0.73 ± 0.16 | 0.02 | 0.65 ± 0.22 | 0.67 ± 0.21 | 0.02 | |
| Group 6 | 0.68 ± 0.16 | 0.73 ± 0.13 | 0.05* | 0.67 ± 0.22 | 0.72 ± 0.18 | 0.05* | 0.76 ± 0.15 | 0.79 ± 0.13 | 0.04 | |
| Group 7 | 0.57 ± 0.19 | 0.65 ± 0.17 | 0.08* | 0.67 ± 0.20 | 0.68 ± 0.20 | 0.01 | 0.59 ± 0.24 | 0.69 ± 0.21 | 0.10* | |
| Fibrosis score | Group 2 | 0.30 ± 0.24 | 0.65 ± 0.20 | 0.36* | 0.21 ± 0.19 | 0.62 ± 0.22 | 0.41* | 0.83 ± 0.28 | 0.78 ± 0.21 | -0.03 |
| Group 3 | 0.45 ± 0.28 | 0.65 ± 0.24 | 0.50* | 0.36 ± 0.26 | 0.63 ± 0.25 | 0.27* | 0.84 ± 0.19 | 0.76 ± 0.23 | -0.08* | |
| Group 4 | 0.46 ± 0.22 | 0.65 ± 0.19 | 0.18* | 0.39 ± 0.24 | 0.69 ± 0.21 | 0.30* | 0.76 ± 0.26 | 0.67 ± 0.26 | -0.08* | |
| Group 5 | 0.42 ± 0.28 | 0.62 ± 0.23 | 0.20* | 0.34 ± 0.17 | 0.61 ± 0.24 | 0.27* | 0.76 ± 0.28 | 0.70 ± 0.21 | -0.05 | |
| Group 6 | 0.29 ± 0.31 | 0.63 ± 0.21 | 0.34* | 0.23 ± 0.27 | 0.60 ± 0.26 | 0.37* | 0.81 ± 0.29 | 0.75 ± 0.20 | -0.05 | |
| Group 7 | 0.04 ± 0.09 | 0.64 ± 0.19 | 0.59* | 0.02 ± 0.60 | 0.58 ± 0.21 | 0.55* | 0.83 ± 0.33 | 0.78 ± 0.16 | -0.02 | |
Data are presented as the mean ± standard deviation of the spatial overlap accuracy metrics of the CT slices.
*Indicates that the difference in the overlap accuracy metrics between (1) and (2) is statistically significant (P < 0.008). P-values were calculated using paired t-tests. Significance level of 0.008 takes into account the Bonferroni correction for multiple tests, †The mean pixel-wise precision of the original and converted CT images was calculated for those CT slices for which pixel-wise precision was available for both the original and converted CT images, ‡The difference in pixel-wise precision between the original and converted CT images and its statistical significance were calculated for those CT slices for which pixel-wise precision was available for both the original and converted CT images.
CT = computed tomography, DSC = dice similarity coefficient