TABLE 1.
CTL epitopes identified in patients infected with HIV-1
| HLA restriction | Protein | Amino acid positions | Clade | Consensus sequence |
|---|---|---|---|---|
| HLA-A*201 | p17gag | 77–85 | A | SLFNTVATL |
| B | --Y------ | |||
| C | --?------ (F/H/Y at position 3) | |||
| D | --Y------ | |||
| HLA-Cw4 | p17gag | 21–40 | A | LRPGGKKKYRLKHLVWASRE |
| B | -------K-KL--I------ | |||
| C | -------h-MI--L------ | |||
| D | -------K-?L--I------ | |||
| HLA-A24 | p24gag | 296–306 | A | RDYVDRFFKTL |
| B | -------Y--- | |||
| C | ----------- | |||
| D | -------Y--- | |||
| HLA-A26 or -B70 | p24gag | 298–306 | A | YVDRFFKTL |
| B | -----Y--- | |||
| C | --------- | |||
| D | -----Y--- | |||
| HLA-B*8101 | p24gag | 179–188 | A | SALSEGATPQDLNMMLNIVG |
| B | -------------T---T-- | |||
| C | -------------T---T-- | |||
| D | -------------T---T-- | |||
| HLA-B70 | Pol (RTa) | 470–478 | A | DVKQLTEVV |
| B | -------A- | |||
| C | --?---?-- | |||
| D | -----A-A- |
a
RT, reverse transcriptase.