Fig. 2.

Functional characteristics of differentially expressed proteins. Given are representative enriched Gene Ontology and biological pathway (KEGG/Reactome) terms for differentially upregulated (UR) and downregulated (DR) protein lists in each of the following cases: (i) old vs. young baseline; (ii) post-resistance exercise training (RET) vs. baseline (i.e. pre-RET) in young muscle; and (iii) post-RET vs. baseline in old muscle. Strength of colour shading depicts magnitude of enrichment significance, given by the negative log10 of that term’s enrichment false discovery rate (FDR) P-value (with darker shading analogous with a stronger FDR P-value). Numbers of enriched proteins in each case are given in associated heatmap boxes