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. 2023 Feb 24;45(3):1411–1438. doi: 10.1007/s11357-023-00748-y

Graphical abstract.

Graphical abstract

Alzheimer’s disease (AD) pathology leads to the release of Aβ peptides, and their accumulation in the peripheral organs has varying effects on various components of the cardiovascular system including endoplasmic reticulum (ER) stress and vascular damage. Image created with BioRender.com