Table 4.

A comparative evaluation of NRI and IDI in predictive models for 28-day mortality in geriatric individuals with ischemic stroke.

Index	Development dataset			Validation dataset
	Estimate	95% CI	P-value	Estimate	95% CI	P-value
NRI (vs. SOFA)	0.304	0.225–0.384	< 0.001	0.333	0.218–0.448	< 0.001
NRI (vs. APS III)	0.205	0.123–0.286	< 0.001	0.107	0.038–0.251	0.148
NRI (vs. LODS)	0.244	0.162–0.327	< 0.001	0.257	0.135–0.379	< 0.001
NRI (vs. SAPS II)	0.275	0.193–0.357	< 0.001	0.190	0.047–0.333	0.009
NRI (vs. OASIS)	0.209	0.133–0.285	< 0.001	0.160	0.024–0.297	0.022
IDI (vs. SOFA)	0.201	0.169–0.232	< 0.001	0.164	0.114–0.213	< 0.001
IDI (vs. APS III)	0.126	0.096–0.157	< 0.001	0.067	0.013–0.121	0.016
IDI (vs. LODS)	0.146	0.115–0.177	< 0.001	0.121	0.071–0.171	< 0.001
IDI (vs. SAPS II)	0.155	0.121–0.188	< 0.001	0.094	0.039–0.149	0.001
IDI (vs. OASIS)	0.118	0.090–0.146	< 0.001	0.062	0.012–0.112	0.014

NRI net reclassification index, IDI integrated discrimination improvement, CI confidence interval, SOFA sequential organ failure assessment, APS III acute physiology score III, LODS logistic organ dysfunction system, SAPS II simplified acute physiology score II, OASIS Oxford acute severity of illness score.

Cutoff: 0, 0.4, 0.8, 1.