. 2023 May 15;31(8):895–904. doi: 10.1038/s41431-023-01379-9

Table 3.

Summary of the genotype–phenotype correlations in patients with a MYT1L microduplication.

Clinical phenotype	Genomic composition of the microduplication and position within MYT1L
Clinical phenotype	Intragenic*	5′ end multiexon^a	3′ end multiexon^a	multigenic^b microduplication	Fisher-Freeman-Halton Exact test (p value)
Schizophrenia	0% (0/10)	0% (0/10)	0% (0/10)	100% (10/10)	0.003^c
ID/DD	9% (1/11)	55% (6/11)	0% (0/11)	36% (4/11)
ASD	37% (3/8)	0% (0/8)	0% (0/8)	63% (5/8)
No neuropsychiatric phenotype	27% (3/11)	9% (1/11)	18% (2/11)	46% (5/11)
Prenatal cases	0% (0/2)	0% (0/2)	0% (0/2)	100% (2/2)
All	17% (7/42)	17% (7/42)	4% (2/42)	62% (26/42)

^aMicroduplications involving only MYT1L gene.

^bMYT1L microduplications extending to neighboring genes.

^cSignificative p value.