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Effects of T22, TW70, and T134 on T-tropic or M-tropic HIV-1-infected MAGI-CCR5 cells
| Compound and concn (μg/ml) | No. of blue cells (mean ± SD)a
|
|
|---|---|---|
| T-tropic HIV-1b | M-tropic HIV-1c | |
| None | 296 ± 5 | 430 ± 8 |
| T22 | ||
| 10 | 0 ± 0 | 377 ± 33 |
| 0.1 | 13 ± 3 | 347 ± 82 |
| TW70 | ||
| 10 | 4 ± 1 | 337 ± 7 |
| 0.1 | 6 ± 2 | 372 ± 60 |
| T134 | ||
| 10 | 5 ± 2 | 372 ± 75 |
| 0.1 | 3 ± 1 | 328 ± 68 |
The MAGI assay was performed as described by Kimpton and Emerman (17), except that DEAE-dextran was not used.
HIV-1IIIB.
HIV-1JR-FL.
