Table 1.
Characteristics of the study population and clinical data distribution.
| Total (N = 7907) | Non-ObCAD (N = 4204) | ObCAD (N = 3703) | p-value | |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age, years | 63.6 (12.5) | 60.9 (12.9) | 66.7 (11.4) | < 0.01 |
| Male | 4847 (61.3) | 2304 (54.8) | 2544 (68.7) | < 0.01 |
| Medical history and social history | ||||
| Diabetes mellitus | 2420 (30.6) | 933 (22.2) | 1485 (40.1) | < 0.01 |
| Hypertension | 4515 (57.1) | 2144 (51.0) | 2370 (64.0) | < 0.01 |
| Dyslipidemia | 1083 (13.7) | 584 (13.9) | 500 (13.5) | 0.66 |
| Smoking | < 0.01 | |||
| Nonsmoker | 5005 (63.3) | 2804 (66.7) | 2207 (59.6) | |
| Past smoker | 981 (12.4) | 446 (10.6) | 533 (14.4) | |
| Current smoker | 1921 (24.3) | 954 (22.7) | 967 (26.1) | |
| Physical measurements | ||||
| Systolic blood pressure, mmHg | 137.7 (21.6) | 136.5 (21.4) | 138.9 (21.8) | 0.03 |
| Diastolic blood pressure, mmHg | 81.4 (13.5) | 82.0 (13.5) | 80.7 (13.5) | < 0.01 |
| Body mass index, kg/m2 | 24.8 (3.6) | 24.9 (3.7) | 24.6 (3.6) | < 0.01 |
| Laboratory findings | ||||
| White blood cell count, × 109/L | 6.5 (5.3–8.1) | 6.3 (5.2–7.8) | 6.8 (5.6–8.5) | < 0.01 |
| Hemoglobin, g/dL | 13.5 (2.0) | 13.7 (1.9) | 13.3 (2.1) | < 0.01 |
| Platelet count, × 109/L | 227.7 (65.3) | 230.6 (63.3) | 224.1(67.4) | < 0.01 |
| Total cholesterol, mg/dL | 163 (136–192) | 170 (143–196) | 156 (128–187) | < 0.01 |
| Triglyceride, mg/dL | 115 (83–166) | 112 (80–164) | 120 (86–169) | < 0.01 |
| LDL cholesterol, mg/dL | 99 (75–127) | 104 (81–130) | 93 (70–122) | < 0.01 |
| HDL cholesterol, mg/dL | 45 (38–55) | 48 (39–58) | 43 (36–41) | < 0.01 |
| BUN, mg/dL | 15.4 (12.3–19.7) | 14.8 (12.0–18.6) | 16.1 (12.8–21.2) | < 0.01 |
| Creatinine, mg/dL | 0.9 (0.8–1.1) | 0.9 (0.7–1.0) | 1.0 (0.8–1.2) | < 0.01 |
| eGFR by CKD-EPI, mL/min/1.73 m2 | 86 (69–97) | 90 (74–99) | 82 (61–93) | < 0.01 |
| Glucose, mg/dL | 110 (97–138) | 107 (96–129) | 116 (100–150) | < 0.01 |
| HbA1c, % | 5.9 (5.6–6.6) | 5.8 (5.5–6.3) | 6.1 (5.7–7.0) | < 0.01 |
| AST, IU/L | 23 (19–31) | 23 (19–31) | 23 (19–31) | 0.33 |
| ALT, IU/L | 21 (15–31) | 21 (16–31) | 21 (15–31) | 0.13 |
| Ratio 1 | 0.8 (0.5–1.1) | 0.8 (0.5–1.0) | 1.0 (0.7–1.2) | < 0.01 |
| Ratio 2 | 4.9 (3.5–6.4) | 5.2 (3.8–6.8) | 4.5 (3.3–6.0) | < 0.01 |
| Ratio 3 | 0.9 (0.5–1.4) | 0.9 (0.4–1.3) | 1.0 (0.6–1.5) | < 0.01 |
| hsCRP, mg/dL | 0.1 (0.1–0.6) | 0.1 (0.1–0.5) | 0.2 (0.1–0.7) | < 0.01 |
Values are presented as means (standard deviations) or medians (interquartile ranges) for continuous variables and proportions (%) for categorical variables.
LDL low density lipoprotein, HDL high density lipoprotein, eGFR estimated glomerular filtration rate, CKD-EPI chronic kidney disease epidemiology collaboration, HbA1c hemoglobin A1c, AST aspartate aminotransferase, ALT alanine transaminase, hsCRP high sensitivity C-reactive protein.
Ratio 1: monocyte/HDL cholesterol, ratio 2: lymphocyte/monocyte, ratio 3: log(triglyceride/HDL-cholesterol).