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. 2023 Aug 3;14:4655. doi: 10.1038/s41467-023-40349-z

Table 3.

Adverse events in neoadjuvant therapy and surgery

Type of event No. of patients
All grades (%) Grade ≥ 3 (%)
Adverse event (n = 47) 47 (100.0) 3 (6.4)
Diarrhea 37 (78.7) 1 (2.1)
Rash 37 (78.7) 0 (0.0)
Stomatitis 32 (68.1) 0 (0.0)
Paronychia 24 (51.1) 0 (0.0)
Anorexia and nausea 12 (25.5) 0 (0.0)
Fatigue 11 (23.4) 0 (0.0)
Pruritus 10 (21.3) 0 (0.0)
Dry skin 4 (8.5) 0 (0.0)
Interstitial pneumonia 3 (6.4) 1 (2.1)
Elevated ALT 3 (6.4) 1 (2.1)
Surgical-related complications (n = 33)
Prolonged air leakage 3 (9.1) 0 (0.0)
Bronchopleural fistula 1 (3.0) 0 (0.0)

ALT alanine aminotransferase.