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. 2023 Aug 3;14:4668. doi: 10.1038/s41467-023-40047-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Upper panel: Schematic representation of the experimental design. Bottom panel: Representative H&E from at least four independent mice showing CHIKV-infected WT, Mavs^+/− and Mavs^−/− hearts at 10 dpi. Scale = 200 μm. The black square indicates the section selected (inset i and ii). Inset i: myocardial region. Inset ii: large vessels attached to the base of the heart. Scale = 20 μm. b Quantification of the number of mice with positive signs of myocarditis. Data represent the percentage of mice with any sign of myocarditis over the total amount of mice analyzed. WT (n = 4), Mavs^+/− (n = 6), and Mavs^−/− (n = 13). c Quantification of the number of mice with large vessel vasculitis. Data represent the percentage of mice with any sign of vasculitis over the total amount of mice analyzed. WT (n = 4), Mavs^+/− (n = 6), and Mavs^−/− (n = 13). Created with BioRender.com. Source data are provided as a source data file (Related to Supplementary Data 1).