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. 2023 Feb 16;45(3):1491–1510. doi: 10.1007/s11357-023-00735-3

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© The Author(s), under exclusive licence to American Aging Association 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 4 — Cerebral vascular oxygenation. (a) Comparison of the PO₂ measurements (a) performed in the arterioles (A) and venules (V) selected within the top 100-µm depth under the cortical surface. This analysis was made with the measurements performed in n = 4 control mice (Ctrl; in total 90 and 166 samples acquired in the arterioles and venules, respectively), and n = 6 WBI-treated mice (WBI; in total 153 and 252 samples acquired in the arterioles and venules, respectively). (b) Comparison of SO₂ calculated based on the PO₂ data from the panel (a). (c) Comparison of OEF calculated based on the SO₂ data from the panel (b). The data were first averaged over the vessels in each mouse and then over mice. Data are expressed as mean ± STD. No significant difference was observed in this analysis (Student’s t-test)