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. 2015 Jan 25;44(6):603–610, 617. [Article in Chinese] doi: 10.3785/j.issn.1008-9292.2015.11.02

表3 静脉溶栓后SBP(每变化10 mm Hg)与患者3个月神经功能结局不良的多因素分析

Table 3 Multivariate regression analysis of systolic blood pressure variability (per 10 mm Hg) and long-term clinical outcome in acute ischemic stroke patients receiving thrombolysis

因素

回归系数

标准误

OR

95% CI

P

基线SBP

-0.008

0.087

0.992

0.837~1.176

0.928

SBPmean

0.173

0.122

1.189

0.936~1.509

0.156

SBPsd

0.629

0.544

1.875

0.645~5.447

0.248

SBPsv

1.925

0.550

6.853

2.333~20.133

<0.001

SBPsv-rise

1.873

0.480

6.508

2.539~16.682

<0.001

SBPsv-drop

1.113

0.436

3.044

1.296~7.149

0.011

SBPsv(校正SBPmean)

1.853

0.559

6.381

2.132~19.096

0.001

SBPsv-rise(校正SBPmean)

1.725

0.489

5.615

2.152~14.654

<0.001

SBPsv-drop(校正SBPmean)

1.102

0.443

3.009

1.263~7.169

0.013

 多因素分析模型校正因素包括年龄、性别、基线血糖水平、基线NIHSS评分、发病至溶栓时间、基线梗死核心区体积、高血压病史、糖尿病史、心房颤动史、高脂血症史、短暂性脑缺血发作/卒中病史.