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Characterization and construction of 3WJ RNA nanoparticles carrying the α9-nAChR aptamer linked to Alexa 647 or anti-miR-21
The size distribution (left) and zeta potential (center) of 3WJ-Alexa (A), 3WJ-C-α9-apt-Alexa (B), 3WJ-B-α9-apt-Alexa (C), 3WJ-B-α9-anti-scr (D), and 3WJ-B-α9-anti-miR-21 (E) RNA nanoparticles by DLS measurements are shown. The stepwise self-assembly (right) of all of these RNA nanoparticles was evaluated by 8% TBE native PAGE.
