Table 1.
Baseline characteristics of patients meeting high-risk criteria as observed in electronic medical records.
| Already diagnosed | Newly diagnosed | Undiagnosed | |
|---|---|---|---|
| Cohort totalsa, n | 54,580 | 16,012 | 40,202 |
| Age by index date, mean (SD) | 68.7 (10.6) | 67.1 (11.1) | 63.6 (11.9) |
| Female, n (% of cohort) | 31,821 (58.3) | 9406 (58.7) | 24,437 (60.8) |
| Race and Ethnicity, n (% of cohort) | |||
| White | 42,553 (78.0) | 12,346 (77.1) | 28,642 (71.2) |
| Black | 5083 (9.3) | 1552 (9.7) | 9117 (22.7) |
| Other Races/Not recorded | 5992 (11) | 1798 (11.2) | 1982 (5) |
| Hispanic | 952 (1.7) | 316 (2) | 461 (1.1) |
| Smoking, n (% of cohort) | |||
| Current Smoker | 16,069 (29.4) | 5141 (32.1) | 6668 (16.6) |
| Ex-Smoker | 19,257 (35.3) | 4734 (29.6) | 27,316 (67.9) |
| Clinically diagnosed comorbidities (ever), n (% of cohort) | |||
| Diabetes type 2 | 16,499 (30.2) | 4699 (29.3) | 11,523 (28.7) |
| Osteoporosis | 7404 (13.6) | 1602 (10) | 2893 (7.2) |
| Hypertension | 34,571 (63.3) | 9266 (57.9) | 25,491 (63.4) |
| Chronic kidney disease | 8194 (15) | 2146 (13.4) | 4665 (11.6) |
| Depression/Anxiety | 25,713 (47.1) | 885 (22.2) | 30,142 (28.5) |
| Congestive Heart Disease | 19,968 (36.6) | 4799 (30) | 9943 (24.7) |
| Obstructive Sleep Apnea | 9942 (18.2) | 2260 (14.1) | 10,097 (25.1) |
| Gastroesophageal reflux disease (GERD) | 22,293 (40.8) | 5336 (33.3) | 13,333 (33.2) |
| Anemia | 12,163 (22.3) | 3020 (18.9) | 6858 (17.1) |
| Major cardiac events, n (% of cohort) | 5289 (9.7) | 1542 (9.6) | 3140 (7.8) |
| BMI recorded within 5 years of index date, n (% of cohort) | |||
| Underweight (<18.5) | 1963 (3.6) | 444 (2.8) | 309 (0.8) |
| Normal weight (18.5–24) | 12,907 (23.6) | 3409 (21.3) | 6171 (15.3) |
| Overweight (25–29) | 14,657 (26.9) | 4160 (26) | 11,159 (27.8) |
| Obese (30.0+) | 22,493 (41.2) | 6760 (42.2) | 21,822 (54.3) |
| Missing BMI | 3113 (5.7) | 1222 (2.4) | 1069 (2.0) |
a
See Supplementary Table S4 for further baseline characteristics.