Table 2.
Summary of included study characteristics.
| Author, year | Exposed | Controls | Age (yrs)a | Study periodb | Strength | Scoring | Comparators |
|---|---|---|---|---|---|---|---|
| Van Meer, 2016 | n = 143 94 M:49F |
No | 25.2 (21.4–32.6) | B/L: <6mo FU: 2 yrs |
1T, 1.5T, 3T | MOAKS | TAS, clinical exam, B/L MRI |
| Wang, 2017 | n = 28 17 M:11F |
n = 9 4 M:5F |
29.8 (SD 6.3) | B/L: 2–3yrs FU: 2 yrs |
3T | T2 | ICRS, B/L MRI |
| Lansdown, 2017 | n = 38 21 M:17F |
Contra-lateral knee | 29.0 (SD 8.0) | B/L: <6mo FU: 1yr |
3T | SSM | SSD, B/L MRI |
| Pietrosimone, 2018 | n = 18 8 M:10F |
Contra-lateral knee | 22.4 (SD 4.2) | B/L: <2wks FU: 1yr |
3T | T1rho | KOOS |
| Zhong, 2019 | n = 30 15 M:15F |
n = 13 5 M:8F |
32.0 (SD 8) | B/L: NS FU: 6mo, 1,2,3yrs |
3T | SSM, WORMS | T1rho, T2, KOOS, previous MRI |
| Culvenor, 2019 | n = 117 85 M:32F |
No | 28.2 (SD 4.9) | B/L: <4wks FU: 2,5yrs |
1.5T | Cartilage thickness (PF) | Previous MRI |
| Struglics, 2020 | n = 116 86 M:30F |
No | 28.2 (SD 4.9) | B/L: <4wks FU: 2,5yrs |
1.5T | ACLOAS | KOOS, SF-36, molecular biomarkers |
| Li, 2020 | n = 34 17 M:17F |
Yes | 30.7 (SD 8) | B/L: <3mo FU: 6mo, 1,2,3yrs |
3T | TT, TR | T1rho, T2, WORMS, previous MRI |
| Friedman, 2021 | n = 35 19 M:16F |
No | 31.0 (SD 7.6) | B/L: NS FU: 6mo, 1,2,3yr |
3T | T1rho, WORMS | MARS, KOOS, previous MRI |
| Xie, 2021 | n = 114 108 M:6F |
n = 43 38 M:5F |
26.2 (SD 3.8) | 2yrs (retrospective) | 3T | Radiomics modelling | T2 |
| Wirth, 2021 | n = 117 85 M:32F |
No | 28.2 (SD 4.9) | B/L: <4wks FU: 2,5yrs |
1.5T | Cartilage thickness (FT) | Previous MRI |
M: Male, F: Female, Mo: Month, yrs: Years, wks: Weeks, T: Telsa, B/L: Baseline, FU: Follow up, MRI: Magnetic Resonance Imaging, OA: Osteoarthritis, MOAKS: MRI OA Score, TAS: Tegner Activity Scale, ICRS: International Cartilage Repair Society, SSM: Statistical Shape Modelling, SSD: Side-to-Side Difference, T2: Transverse relaxation time, T1rho: spin-lattice relaxation time constant in rotating frame, WORMS: Whole-Organ MRI Score, PF: Patellofemoral, ACLOAS: Anterior Cruciate Ligament OA Score, KOOS: Knee OA Outcome Score, SF-:36: Short Form 36 questions, TT: Tibial translation, TR: Tibial Rotation, MARS: Marx Activity Rating Scale, FT: Femorotibial.
Age of injured participants only, reported in Mean (SD) with exception of Van Meer 2016 which is reported as Median (Range).
Baseline signifies time from injury to recruitment, follow-up reports time from recruitment.